Current Vacancies
-
Key details
- Location: UK DRI at Edinburgh, Edinburgh
- Salary: £40,497 - £48,149 per annum
- Lab: Dr Rikesh Rajan
We are looking for a postdoctoral Research Fellow to join the Rajani Lab as part of the new national BHF-UK DRI Centre for Vascular Dementia Research.
The Opportunity:
The Rajani Lab investigates the mechanisms of white matter damage in vascular and other dementias. We use a range of innovative methodologies and models to understand oligodendrocyte changes in vascular disease, and the interaction of these with neuronal activity. In this project the Research Fellow will use advanced techniques to investigate and manipulate neuronal activity in rodent models of vascular dementia, with the aim of understanding how this affects white matter.
Your skills and attributes for success:
- A PhD (or close to completion) in neuroscience or other relevant discipline.
- Extensive experience with in vivo two-photon calcium imaging.
- Ability to work independently.
- Proactive and creative independent thinker.
- Ability to problem-solve and troubleshoot technical difficulties.
-
Key details
- Location UK DRI at UCL
- Salary: £35,930-£41,255 per annum
- Lab: Dr. Tim Bartels
About us
The UK Dementia Research Institute (UK DRI), a globally leading multidisciplinary research institute of over 900 staff investigating the spectrum of neurodegenerative disorders causing dementia, is the biggest UK initiative supporting research to fill this gap.
The Bartels Lab at the UK DRI at UCL specializes in the study of synuclein multimers and lipidomics in the context of Parkinson’s disease (PD). The lab plays a unique role in this field, addressing key research gaps through close collaborations with the National Hospital for Neurology and Neurosurgery and the Queen Square Brain Bank.
Dr Tim Bartels first discovered disease resistant forms of the α-synuclein protein and their destabilization in Parkinson’s Disease. His lab is interested in identifying the different factors that destabilize α-synuclein and that lead to neurotoxicity.
About the role
We are seeking a Research Technician to contribute to a project involving advanced murine models of synucleinopathies, especially the gut-brain axis in Parkinson’s Disease.
You will provide technical assistance with in vivo experimental work, histopathology techniques, biochemical analysis such as Western Blot and ELISA.
The post is available from 01 October 2025 and is funded by UK DRI at UCL for one year in the first instance.
About you
You will have an Honours degree (minimum 2:1) or equivalent in Biophysics, Biochemistry, Molecular Biology or a related discipline, and experience with iPSC culture and neuronal differentiation. A background and knowledge in one or more of the following is essential: Neurodegeneration, synucleinopathies, biochemical analysis, such as detergent extraction and Western Blot, IHC. Experience of working with Biophysics, Biochemistry, Molecular Biology, Histology assays is also a requirement, as is an understanding of the mission of the UK DRI, an interest in its research work and a commitment to supporting high quality research.