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Research Fellow in Immunity in Alzheimer’s Disease

Location

UK DRI at UCL

Deadline

Jul 27, 2025

About the role

We are looking for a motivated postdoctoral researcher to join our team investigating how Alzheimer’s disease (AD) risk genes influence microglial function in disease. The project focuses on the antigen-presenting role of microglia in amyloid pathology and the immunological impact of MHC-II–mediated responses in the brain.

You will use a wide range of techniques, including our unique human microglia xenograft model (PMID: 31659342, 38539015), and work closely with both computational and experimental teams at the Francis Crick Institute and VIB, Leuven.

This is a unique opportunity to contribute to high-impact research in a world-class, collaborative environment.

About you

You’ll have a PhD in Immunology, Neuroscience, or a related field, with experience with macrophage and/or microglia biology and knowledge of molecular biology, cell biology, immunology, or related disciplines, as well as proficiency in cell culture and cell biology techniques, with a strong understanding of immunology and/or antigen presentation.

Experience with animal experiments, particularly in handling and working with mice is also essential for this role.

Key details

  • Location UK DRI at UCL
  • Salary: £43,374 £51,860
  • Lab: Dr Lorena Arancibia