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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Plasma proteomic analysis identifies proteins and pathways related to Alzheimer's risk

Authors
Yen-Ning Huang, Shiwei Liu, Tamina Park, Soumilee Chaudhuri, Lindsey A Kuchenbecker, Minerva M Carrasquillo, Nilüfer Ertekin-Taner, Paula J Bice, Henrik Zetterberg, Kaj Blennow, Kristen Russ, Jeffrey L Dage, Kelly N H Nudelman, Carlos Cruchaga, Jared R Brosch, Martin R Farlow, David G Clark, Sunu Mathew, Frederick Unverzagt, Sujuan Gao, Sophia Wang, Liana G Apostolova, Donna M Wilcock, Tatiana Foroud, Shannon L Risacher, Andrew J Saykin, Kwangsik Nho
Plasma proteomic analysis identifies proteins and pathways related to Alzheimer's risk
Brain : a journal of neurology
Published

Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease

Authors
Hannah de Bruin, Colin Groot, Henryk Barthel, Gérard N Bischof, Ganna Blazhenets, Ronald Boellaard, Baayla D C Boon, Matthias Brendel, David M Cash, William Coath, Gregory S Day, Bradford C Dickerson, Elena Doering, Alexander Drzezga, Christopher H van Dyck, Thilo van Eimeren, Wiesje M van der Flier, Carolyn A Fredericks, Tim D Fryer, Elsmarieke van de Giessen, Brian A Gordon, Jonathan Graff-Radford, Lea T Grinberg, Oskar Hansson, Diana A Hobbs, Merle C Hoenig, Günter Höglinger, David J Irwin, P Simon Jones, Keith A Josephs, Yuta Katsumi, Renaud La Joie, Edward B Lee, Johannes Levin, Maura Malpetti, Scott M McGinnis, Adam P Mecca, Rosaleena Mohanty, Ilya M Nasrallah, John T O'Brien, Ryan S O'Dell, Carla Palleis, Robert Perneczky, Jeffrey S Phillips, Deepti Putcha, Gil D Rabinovici, Nesrine Rahmouni, Pedro Rosa-Neto, James B Rowe, Michael Rullmann, Osama Sabri, Dorothee Saur, Andreas Schildan, Jonathan M Schott, Matthias L Schroeter, William W Seeley, Stijn Servaes, Irene Sintini, Ruben Smith, Salvatore Spina, Jenna Stevenson, Erik Stomrud, Olof Strandberg, Joseph Therriault, Pontus Tideman, Alexandra Touroutoglou, Anne E Trainer, Denise Visser, Fattin Wekselman, Philip S J Weston, Jennifer L Whitwell, David A Wolk, Keir Yong, Yolande A L Pijnenburg, Nicolai Franzmeier, Rik Ossenkoppele
Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease
Nature
Published

The genomic origin of the unique chaetognath body plan

Authors
Laura Piovani, Daria Gavriouchkina, Elise Parey, Luke A Sarre, Katja T C A Peijnenburg, José María Martín-Durán, Daniel S Rokhsar, Noriyuki Satoh, Alex de Mendoza, Taichiro Goto, Ferdinand Marlétaz
The genomic origin of the unique chaetognath body plan
The journal of prevention of Alzheimer's disease
Published

Blood pressure and Alzheimer's disease biomarkers in cognitively unimpaired adults: a multicenter study

Authors
Mariona Osset-Malla, Aitana Martínez-Velasco, Gonzalo Sánchez-Benavides, Mariateresa Buongiorno, Alejandro de la Sierra, Mahnaz Shekari, Carolina Minguillon, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Henrik Zetterberg, Kaj Blennow, David Vállez García, Marc Suárez-Calvet, Juan Domingo Gispert, Oriol Grau-Rivera, ALFA Study
Blood pressure and Alzheimer's disease biomarkers in cognitively unimpaired adults: a multicenter study
The European journal of neuroscience
Published

Amyloid-Beta Pathology Increases Synaptic Engulfment by Glia in Feline Cognitive Dysfunction Syndrome: A Naturally Occurring Model of Alzheimer's Disease

Authors
Robert I McGeachan, Lucy Ewbank, Meg Watt, Lorena Sordo, Alexandra Malbon, Muhammad Khalid F Salamat, Makis Tzioras, Joao Miguel De Frias, Jane Tulloch, Fiona Houston, Danièlle Gunn-Moore, Tara L Spires-Jones
Amyloid-Beta Pathology Increases Synaptic Engulfment by Glia in Feline Cognitive Dysfunction Syndrome: A Naturally Occurring Model of Alzheimer's Disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology

Authors
Laia Montoliu-Gaya, Elizabeth Valeriano-Lorenzo, Nicholas J Ashton, Francisco J López-González, Juan Lantero-Rodriguez, Alicia Ruiz-González, Ana Belén Pastor, Belen Frades, María Ascensión Zea-Sevilla, Meritxell Valentí, Paloma Ruiz-Valderrey, Laura Saiz, Iván Burgueño-García, Maria José López-Martínez, Teodoro Del Ser, Gunnar Brinkmalm, Henrik Zetterberg, Alberto Rábano, Johan Gobom, Kaj Blennow, Pascual Sánchez-Juan
Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology
Alzheimer's & dementia (New York, N. Y.)
Published

More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles

Authors
Mackenzie Jarchow, Ira Driscoll, Brianne M Breidenbach, Noah Cook, Catherine L Gallagher, Sterling C Johnson, Sanjay Asthana, Bruce P Hermann, Mark A Sager, Kaj Blennow, Henrik Zetterberg, Cynthia M Carlsson, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Dane B Cook, Dena B Dubal, Ozioma C Okonkwo
More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles
Alzheimer's research & therapy
Published

Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups

Authors
Heekyoung Kang, Heejin Yoo, Jungah Lee, Soyeon Yoon, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Theresa A Day, Sung Hoon Kang, Jihwan Yun, Min Young Chun, Eun Hye Lee, Jun Pyo Kim, Hee Jin Kim, Duk L Na, Hyemin Jang, Daeun Shin, Sang Won Seo, K-ROAD study group
Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published

Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease

Authors
Gordon W Blair, Ian J C MacCormick, Sarah McGrory, Tom MacGillivray, Iona Hamilton, Yulu Shi, Francesca Chappell, Michael J Thrippleton, Michael S Stringer, Fergus Doubal, Joanna M Wardlaw
Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease
European journal of nuclear medicine and molecular imaging
Published

Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles

Authors
Daeun Shin, Hyemin Jang, Heejin Yoo, Kyungmin Kim, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Eun Hye Lee, Jihwan Yun, Duk L Na, Hee Jin Kim, Sung Hoon Kang, Ko Woon Kim, Si Eun Kim, Yeo Jin Kim, Yeshin Kim, Min Young Chun, Na Yeon Jung, Soo Hyun Cho, Jun Pyo Kim, Sang Won Seo, K-ROAD study groups
Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia-specific perspectives

Authors
Takeshi Iwatsubo, Reisa A Sperling, Alicia Algeciras-Schimnich, Hidenori Arai, Anna M Barron, Tammie L S Benzinger, Maria C Carrillo, Christopher Chen, Seong Hye Choi, Igor C Fontana, Jonathan Graff-Radford, Joshua D Grill, Judith Heidebrink, Chaur-Jong Hu, Ryoko Ihara, Takeshi Ikeuchi, Atsushi Iwata, Fanny C F Ip, Fasihah Irfani Fitri, Clifford R Jack, Jee Hyang Jeong, Jianping Jia, Nagaendran Kandiah, SangYun Kim, Hisatomo Kowa, Renaud La Joie, Yoshiki Niimi, Ryoji Noritake, Ozioma C Okonkwo, Sebastian Palmqvist, Michael S Rafii, Rema Raman, Yong Shen, Tanya Simuni, Heather M Snyder, Orapitchaya Sriwannopas, Luke E Stoeckel, Wiesje M van der Flier, Huali Wang, Donna M Wilcock, Henrik Zetterberg, Jin Zhou, Simin Mahinrad, Claire E Sexton
Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia-specific perspectives
Annals of clinical and translational neurology
Published

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age- and BMI-Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

Authors
Maximilian Einsiedler, Aleksandra Maleska Maceski, Sofia Sandgren, Johanna Oechtering, Sabine Schaedelin, Lisa Hofer, Amar Zadic, Juan Francisco Vilchez Gomez, Lester Melie-Garcia, Alessandro Cagol, Riccardo Galbusera, Sebastian Finkener, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D'Souza, Lars G Hemkens, Tobias Derfuss, Özgür Yaldizli, Patrick Roth, Claudio Gobbi, David Brassat, Björn Tackenberg, Henrik Zetterberg, Tjalf Ziemssen, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Fredrik Piehl, Ludwig Kappos, Cristina Granziera, Ahmed Abdelhak, David Leppert, Eline A J Willemse, Pascal Benkert, Jens Kuhle, Swiss Multiple Sclerosis Cohort Study (SMSC)
Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age- and BMI-Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response