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Mootaz Salman profile

Dr Mootaz Salman

BPharm, MSc, PhD (he/him)

Group Leader

Deciphering the role of the blood-brain barrier in neurodegeneration

Techniques

Advanced microscopy & imaging, CRISPR, Drug screening, Stem cells / iPSCs

Biography

Dr Mootaz Salman is a Group Leader in Cellular Neuroscience and MRC Career Development Fellow at the University of Oxford, and Principal Investigator at the British Heart Foundation (BHF) Centre for Research Excellence and the UK Dementia Research Institute BHF-UK DRI Centre for Vascular Dementia Research. 

Following a Postdoctoral Fellowship at Harvard Medical School and Boston Children’s Hospital, Dr Salman moved to Oxford in 2020, and he was awarded the Leverhulme Research Fellowship that enabled him to start his independent work as Departmental Research Lecturer. In 2023, he launched his research group at DPAG, which is primarily funded through his MRC Career Development Fellowship, and supported by other grants including BBSRC Pioneer Award, ERC, CONNECT - Horizon2020, Chief Scientist Office Research Grant and the Royal Society. 

His group aims to investigate mechanisms of blood-brain barrier (dys)function in neurodegenerative diseases and brain injuries using patient-derived stem cells. They design and build innovative dynamic 3D multicellular in vitro models and organoids to accurately recapitulate the brain and blood-brain barrier function under mechanobiological stimuli, neuroinflammation and other neurodegenerative-relevant conditions. 

Dr Salman was awarded multiple accolades including the International Society of Neurochemistry (ISN) and APSN Young Neuroscientist Lectureship Award in 2022, The Society for Experimental Biology (SEB) 2024 President’s Medal for the Cell Biology Section, the Alzheimer’s Research UK David Hague Early Career Investigator of the Year in 2024 and the inaugural ALBA-Roche Research Prize for Excellence in Neuroscience 2024.

Salman Lab

Explore the work of the Salman Lab focused on understanding the role of the blood-brain barrier in neurodegeneration.

traumatic brain injury in mice