Abstract
Neuroimaging Clin N Am. 2025 May;35(2):251-265. doi: 10.1016/j.nic.2024.12.003. Epub 2025 Feb 19.
ABSTRACT
MR imaging-visible perivascular spaces (PVS) have been associated with disease phenotypes, risk factors, sleep measures, and overall brain health. We review avenues in the analysis of PVS quantified from brain MR imaging across dissimilar acquisition protocols, imaging modalities, scanner manufacturers and magnetic field strengths. We conduct a pilot analysis to evaluate different avenues to harmonise PVS assessments from using different parameters using brain MR imaging from 100 adult volunteers, acquired at two different magnetic field strengths with different sequence parameters. The 2024 MICCAI Enlarged Perivascular Spaces Segmentation Challenge provides a representative MRI dataset on which to test other harmonization methods.
PMID:40210381 | DOI:10.1016/j.nic.2024.12.003