The global burden of cerebral small vessel disease in low- and middle-income countries: A systematic review and meta-analysis.

Authors

Bonnie Yin Ka Lam, Yuan Cai, Rufus Akinyemi, Geert Jan Biessels, Hilde van den Brink, Christopher Chen, Chin Wai Cheung, King Ngai Chow, Henry Kwun Hang Chung, Marco Duering, Siu Ting Fu, Deborah Gustafson, Saima Hilal, Vincent Ming Ho Hui, Rajesh Kalaria, SangYun Kim, Maggie Li Man Lam, Frank Erik de Leeuw, Ami Sin Man Li, Hugh Stephen Markus, Anna Marseglia, Huijing Zheng, John O'Brien, Leonardo Pantoni, Perminder Singh Sachdev, Eric E Smith, Joanna Wardlaw, Vincent Chung Tong Mok

Abstract

Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. Previous studies on the prevalence of cSVD are mostly based on single geographically defined cohorts in high-income countries. Studies investigating the prevalence of cSVD in low- and middle-income countries (LMICs) are expanding but have not been systematically assessed.

PMID:36282189 | DOI:

UK DRI Authors

Dr Hilde van den Brink

Postdoctoral Researcher

Identifying the mechanisms that drive brain haemorrhages in CAA, with a broader interest in shared disease mechanisms across cerebral small vessel diseases.

Dr Hilde van den Brink

Prof Joanna Wardlaw

Group Leader and Clinical Director of the CVDR

Causes, mechanisms, clinical features, diagnosis, consequences, outcomes and treatment of cerebral small vessel disease focusing on clinical studies.

Prof Joanna Wardlaw