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Scandinavian journal of clinical and laboratory investigation
Published

Influence of pneumatic tube system transport on cell count and spectrophotometry in cerebrospinal fluid

Authors

Marcus Clarin, Joel Simrén, Johanna Svanberg, Hanna Fahlén, Ulf Andreasson, Henrik Zetterberg

Abstract

Scand J Clin Lab Invest. 2025 Dec 17:1-6. doi: 10.1080/00365513.2025.2605636. Online ahead of print.

ABSTRACT

Pneumatic tube systems (PTS) are routinely used in many hospitals for transporting collected body fluid samples and to reduce turnaround time. However, their use for transport of CSF is not widespread, in part due to ambiguous or non-existing data regarding possible impact on sample stability caused by PTS. This study investigates the effect of PTS transport on cell counts in CSF as well as on haemolysis. No statistical differences were observed on cell count for erythrocytes, leukocytes, lymphocytes, neutrophils, or monocytes as well as on haemolysis measured as absorbance at 415 nm. Therefore, it should be possible to use a PTS to transport CSF for these analyses.

PMID:41406336 | DOI:10.1080/00365513.2025.2605636

UK DRI Authors

Profile picture of Henrik Zetterberg

Prof Henrik Zetterberg

Group Leader

Pioneering the development of fluid biomarkers for dementia

Prof Henrik Zetterberg