Skip to main content
Search
Main content
J Neurol Neurosurg Psychiatry
Published

Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70.

Authors

Sarah E Keuss, William Coath, David M Cash, Josephine Barnes, Jennifer M Nicholas, Christopher A Lane, Thomas D Parker, Ashvini Keshavan, Sarah M Buchanan, Aaron Z Wagen, Mathew Storey, Matthew Harris, Kirsty Lu, Sarah-Naomi James, Rebecca Street, Ian B Malone, Carole H Sudre, David L Thomas, John C Dickson, Frederik Barkhof, Heidi Murray-Smith, Andrew Wong, Marcus Richards, Nick C Fox, Jonathan M Schott

Abstract

Consistent patterns of reduced cortical thickness have been identified in early Alzheimer's disease (AD). However, the pathological factors that influence rates of cortical thinning within these AD signature regions remain unclear.

PMID:38199813 | DOI: