Biography
I am currently an Epilepsy Research Insitute Entry Fellow, with the project 'Can non-invasive brain stimulation treat Alzheimer’s Disease related epilepsy?'. The project aims to understand the link between Alzhiemer's Disease and Epilepsy and test a new type of non-invasive brain stimulation, called ‘Temporal Interference’, which can target deep brain areas without affecting surrounding tissueto help reduce seizure activity.
I joined the Barnes Lab (UK DRI) in October 2023. The Barnes lab investigates why the aged brain is vulnerable to neurodegeneration and asks whether we can alleviate this susceptibility, with a focus on homeostatic neural-circuit plasticity processes. My current focus is dissecting the underlying physiological differences which contribute to variable learning across ageing. To investigate this, I use a number of techniques, longitudinal 2-Photon in vivo imaging, in vivo mesoscopic calcium imaging, in vivo electrophysiology, immunofluorescence labelling, behavioural testing and electrical stimulation interventions.
In 2018, I was awarded a prestigious MRC 1 3 PhD programme position at the Centre for Neurodevelopmental Disorders (CNDD), King’s College London. During my PhD with Samuel Cooke (KCL), I investigated the role of inhibitory interneurons in visual cortical plasticity and behavioural habituation using in vivo electrophysiology, optogenetics, chemogenetics and ex vivo electrophysiology. In addition, I used a combination of MATLAB and Python based tools for stimulus generation and data analysis.
Research interest
Learning/ Memory
Plasticity
Epilepsy