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Prof Catherine Hall

(She/Her)

Group Leader

Understanding how changes in blood flow drive onset of disease

Techniques

Advanced microscopy & imaging, Metabolomics, Mouse behaviour, Mouse in vivo imaging, Viral-mediated expression

Biography

Prof Catherine N. Hall’s research focuses on how the brain regulates its blood flow, and how insufficient blood supply to the brain can impact its function and promote dementia. After her undergraduate degree in Physiology with Psychology at the University of Oxford, she moved to University College London for her PhD, under the supervision of Professor John Garthwaite, where she studied the kinetics of nitric oxide signals in brain tissue. She then did a post doc with Professor David Attwell, also at UCL, studying the processes by which oxygen is consumed and supplied to brain, and revealing the importance of capillary pericytes for control of brain blood flow. In 2014 she moved to the University of Sussex to start her lab, and in 2025 rejoined UCL, the UK DRI and the BHF-UK DRI Centre for Vascular Dementia Research, while maintaining a position and lab in Sussex. Her labs use chronic imaging of neurons, glia and blood vessels in mice, alongside biochemical and molecular approaches, to understand how the brain’s blood flow regulation is altered by conditions that increase risk of dementia, and how altering the brain’s oxygen supply affects brain function.

News

Key publications

Mammalian genome : official journal of the International Mammalian Genome Society
Published

Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory

Authors
Mehwish Anwer, Tetiana Poliakova, Ricardo D'Oliveira Albanus, Mohammad Iqbal H Bhuiyan, Adam M Brickman, Soumilee Chaudhuri, Leah Cuddy, Maxwell Eisenbaum, Kate Foley, Douglas B Gould, Catherine Hall, Costantino Iadecola, Olivia Marola, Christopher M Norris, Alaina Reagan, Julie Schneider, Donna Wilcock, Isabella Xu, Andrew Yang, Gareth Howell, Cheryl L Wellington
Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory
Cereb Circ Cogn Behav
Published

A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.

Authors
Sarmi Sri, Adam Greenstein, Alessandra Granata, Alex Collcutt, Angela C C Jochems, Barry W McColl, Blanca Díaz Castro, Caleb Webber, Carmen Arteaga Reyes, Catherine Hall, Catherine B Lawrence, Cheryl Hawkes, Chrysia-Maria Pegasiou-Davies, Claire Gibson, Colin L Crawford, Colin Smith, Denis Vivien, Fiona H McLean, Frances Wiseman, Gaia Brezzo, Giovanna Lalli, Harry A T Pritchard, Hugh S Markus, Isabel Bravo-Ferrer, Jade Taylor, James Leiper, Jason Berwick, Jian Gan, John Gallacher, Jonathan Moss, Jozien Goense, Letitia McMullan, Lorraine Work, Lowri Evans, Michael S Stringer, Mlj Ashford, Mohamed Abulfadl, Nina Conlon, Paresh Malhotra, Philip Bath, Rebecca Canter, Rosalind Brown, Selvi Ince, Silvia Anderle, Simon Young, Sophie Quick, Stefan Szymkowiak, Steve Hill, Stuart Allan, Tao Wang, Terry Quinn, Tessa Procter, Tracy D Farr, Xiangjun Zhao, Zhiyuan Yang, Atticus H Hainsworth, Joanna M Wardlaw
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.