CADASIL Affects Multiple Aspects of Cerebral Small Vessel Function on 7T-MRI.

Authors

Hilde van den Brink, Anna Kopczak, Tine Arts, Laurien Onkenhout, Jeroen C W Siero, Jaco J M Zwanenburg, Sandra Hein, Mathias Hübner, Benno Gesierich, Marco Duering, Michael S Stringer, Jeroen Hendrikse, Joanna M Wardlaw, Anne Joutel, Martin Dichgans, Geert Jan Biessels

Abstract

Cerebral small vessel diseases (cSVDs) are a major cause of stroke and dementia. We used cutting-edge 7T-MRI techniques in patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), to establish which aspects of cerebral small vessel function are affected by this monogenic form of cSVD.

PMID:36222455 | DOI:

UK DRI Authors

Dr Hilde van den Brink

Postdoctoral Researcher

Identifying the mechanisms that drive brain haemorrhages in CAA, with a broader interest in shared disease mechanisms across cerebral small vessel diseases.

Dr Hilde van den Brink