Alzheimers Res Ther
Published

Investigating the relationship between BMI across adulthood and late life brain pathologies.

Authors

Christopher A Lane, Josephine Barnes, Jennifer M Nicholas, John W Baker, Carole H Sudre, David M Cash, Thomas D Parker, Ian B Malone, Kirsty Lu, Sarah-Naomi James, Ashvini Keshavan, Sarah Buchanan, Sarah Keuss, Heidi Murray-Smith, Andrew Wong, Elizabeth Gordon, William Coath, Marc Modat, David Thomas, Rebecca Hardy, Marcus Richards, Nick C Fox, Jonathan M Schott
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Abstract

In view of reported associations between high adiposity, particularly in midlife and late-life dementia risk, we aimed to determine associations between body mass index (BMI), and BMI changes across adulthood and brain structure and pathology at age 69-71 years.

PMID:33941254 | DOI:10.1186/s13195-021-00830-7