Skip to main content
Search
Main content
Transfusion
Published

Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial.

Authors

Zoeb Jiwaji, Kieran P Nunn, Andrew Conway-Morris, A John Simpson, Duncan Wyncoll, Adriano G Rossi, Timothy S Walsh

Abstract

Transfused blood may have immunomodulatory and proinflammatory effects. We report the first randomized study exploring whether leukoreduced red blood cell (RBC) transfusion increases circulating proinflammatory mediators, markers of neutrophil activation, and the acute-phase response in critically ill adults.

PMID:24796937 | DOI:

UK DRI Authors