Skip to main content
Search
Main content
Ann Neurol
Published

Meningeal inflammation and cortical demyelination in acute multiple sclerosis.

Authors

Ryan J Bevan, Rhian Evans, Lauren Griffiths, Lewis M Watkins, Mark I Rees, Roberta Magliozzi, Ingrid Allen, Gavin McDonnell, Rachel Kee, Michelle Naughton, Denise C Fitzgerald, Richard Reynolds, James W Neal, Owain W Howell

Abstract

Cortical gray matter (GM) pathology, involving demyelination and neurodegeneration, associated with meningeal inflammation, could be important in determining disability progression in multiple sclerosis (MS). However, we need to know more about how cortical demyelination, neurodegeneration, and meningeal inflammation contribute to pathology at early stages of MS to better predict long-term outcome.

PMID:30362156 | DOI: