Abstract
Expert Rev Mol Diagn. 2025 May 20. doi: 10.1080/14737159.2025.2509023. Online ahead of print.
ABSTRACT
INTRODUCTION: In this special report, we summarize studies of cerebrospinal fluid and plasma/serum biomarker neurofilament light chain (NfL) concentrations, a key structural component of myelinated axons in neuroinfections.
AREAS COVERED: The following infections were searched for in Pub Med; Neuroinfection and biomarkers, herpes simplex encephalitis and neurofilament light chain, tick-borne encephalitis and neurofilament light chain, Lyme neuroborreliosis and neurofilament light chain, bacterial meningitis and neurofilament light chain, malaria and neurofilament light chain, COVID-19 and neurofilament light chain, HIV infection and neurofilament light chain.
EXPERT OPINION: NfL can serve as a valuable biomarker for assessing disease severity and neurological complications in the acute stage of neuroinfections and can also be useful in evaluating patients with residual symptoms following acute illness.
PMID:40392201 | DOI:10.1080/14737159.2025.2509023
UK DRI Authors
