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European archives of psychiatry and clinical neuroscience
Published

Towards a name change of schizophrenia: Positive and Negative Symptoms Disorder (PND)

Authors

Stefan Leucht, Deniz S Yurtseven, Josef Priller, John M Davis, Jim van Os, Iris E C Sommer

Abstract

Eur Arch Psychiatry Clin Neurosci. 2025 May 19. doi: 10.1007/s00406-025-02018-8. Online ahead of print.

ABSTRACT

We propose renaming schizophrenia to Positive and Negative Symptoms Disorder (PND) to reduce stigma, enhance clarity, and align with current diagnostic criteria. The term reflects core symptom domains, is translatable, ICD compatible, and avoids misleading associations. If cognitive deficits should be part of the name, it would be Positive, Negative, Cognitive Symptoms disorder. Stakeholder input and linguistic evaluation are essential for successful implementation and global acceptance.

PMID:40387871 | DOI:10.1007/s00406-025-02018-8

UK DRI Authors

Josef Priller

Prof Josef Priller

Group Leader

Defining and modulating myeloid cell function in neurodegenerative diseases

Prof Josef Priller