Dr Owen Dando

Senior Bioinformatician

Application of computational techniques, particularly relating to high-throughput sequencing, to neurodegeneration.

Condition

Alzheimer's disease, Frontotemporal dementia, Motor neuron disease/ALS, Vascular dementia

Techniques

Bioinformatics, Genomics, Mass spec-based proteomics, Next generation sequencing, Single cell / nucleus transcriptomics, Software development, Spatial transcriptomics, Statistical modelling

Key publications

Nat Commun
Published
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity.
Authors
Bhuvaneish T Selvaraj, Matthew R Livesey, Chen Zhao, Jenna M Gregory, Owain T James, Elaine M Cleary, Amit K Chouhan, Angus B Gane, Emma M Perkins, Owen Dando, Simon G Lillico, Youn-Bok Lee, Agnes L Nishimura, Urjana Poreci, Sai Thankamony, Meryll Pray, Navneet A Vasistha, Dario Magnani, Shyamanga Borooah, Karen Burr, David Story, Alexander McCampbell, Christopher E Shaw, Peter C Kind, Timothy J Aitman, C Bruce A Whitelaw, Ian Wilmut, Colin Smith, Gareth B Miles, Giles E Hardingham, David J A Wyllie, Siddharthan Chandran
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity.
Nat Commun
Published
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.
Authors
Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C Todd, Samuel Heron, Nóra M Márkus, Jamie McQueen, David W Hampton, Megan Torvell, Sachin S Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J A Wyllie, T Ian Simpson, Giles E Hardingham
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.

Links