Research Technician

About us

The UK Dementia Research Institute (UK DRI), a globally leading multidisciplinary research institute of over 900 staff investigating the spectrum of neurodegenerative disorders causing dementia, is the biggest UK initiative supporting research to fill this gap.

The Bartels Lab at the UK DRI at UCL specializes in the study of synuclein multimers and lipidomics in the context of Parkinson’s disease (PD). The lab plays a unique role in this field, addressing key research gaps through close collaborations with the National Hospital for Neurology and Neurosurgery and the Queen Square Brain Bank.

Dr Tim Bartels first discovered disease resistant forms of the α-synuclein protein and their destabilization in Parkinson’s Disease. His lab is interested in identifying the different factors that destabilize α-synuclein and that lead to neurotoxicity.

About the role

We are seeking a Research Technician to contribute to a project involving advanced murine models of synucleinopathies, especially the gut-brain axis in Parkinson’s Disease.

You will provide technical assistance with in vivo experimental work, histopathology techniques, biochemical analysis such as Western Blot and ELISA.

The post is available from 01 October 2025 and is funded by UK DRI at UCL for one year in the first instance.

About you

You will have an Honours degree (minimum 2:1) or equivalent in Biophysics, Biochemistry, Molecular Biology or a related discipline, and experience with iPSC culture and neuronal differentiation. A background and knowledge in one or more of the following is essential: Neurodegeneration, synucleinopathies, biochemical analysis, such as detergent extraction and Western Blot, IHC. Experience of working with Biophysics, Biochemistry, Molecular Biology, Histology assays is also a requirement, as is an understanding of the mission of the UK DRI, an interest in its research work and a commitment to supporting high quality research.