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Joanna Wardlaw

Prof Joanna Wardlaw

(CBE, MB ChB (Hons), MD, FRCR, FRCP, FMedSci, FRSE (she/her))

Group Leader and Clinical Director of the CVDR

Discovering how small vessel disease damages the brain and what we can do to prevent or treat it

Techniques

Advanced microscopy & imaging, Drug screening, Experimental medicine, Fluid biomarkers, Human brain imaging, Lipidomics, Mass spec-based proteomics, Metabolomics, Mouse behaviour, Mouse in vivo imaging, Single cell / nucleus transcriptomics, Software development, Statistical modelling, Viral-mediated expression

Biography

Prof Joanna Wardlaw, CBE, MB ChB (Hons), MD, FRCR, FRCP, FMedSci, FRSE, is Professor of Applied Neuroimaging at the University of Edinburgh, Foundation Chair of the UK DRI at Edinburgh, Director of the Row Fogo Centre for Research into Ageing and the Brain, and Consultant Neuroradiologist for NHS Lothian. Her work focuses on understanding the brain and its blood supply, and treatments to improve blood flow to the brain, including thrombolytic drugs that are now in routine use to treat stroke, and more recently treatments for small vessel disease and vascular dementia. Working with many colleagues, she has been instrumental in advancing understanding of the causes of cerebral small vessel disease and is now testing treatments in clinical trials. She has set up national research imaging facilities, co-ordinated international research networks, advanced stroke care worldwide and published over 1000 papers. A Fellow of the Royal Society of Edinburgh and the UK Academy of Medical Sciences, she has received awards from many UK and international brain and heart organisations, and was made a Commander of the Order of the British Empire (CBE) for services to Medicine and Neuroscience in 2016.

News

Key publications

bioRxiv : the preprint server for biology
Published
Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates
Authors
Anna E Fürtjes, Isabelle F Foote, Charley Xia, Gail Davies, Joanna Moodie, Adele Taylor, David C Liewald, Paul Redmond, Janie Corley, Andrew M McIntosh, Heather C Whalley, Susana Muñoz Maniega, Maria Valdés Hernández, Ellen Backhouse, Karen Ferguson, Mark E Bastin, Joanna Wardlaw, Javier de la Fuente, Andrew D Grotzinger, Michelle Luciano, W David Hill, Ian J Deary, Elliot M Tucker-Drob, Simon R Cox
Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates
Alzheimer's research & therapy
Published
Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study
Authors
Inga Menze, Jose Bernal, Pinar Kaya, Çağla Aki, Malte Pfister, Jonas Geisendörfer, Renat Yakupov, Roberto Duarte Coello, Maria D C Valdés-Hernández, Michael T Heneka, Frederic Brosseron, Matthias C Schmid, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Ayda Rostamzadeh, Dix Meiberth, Oliver Peters, Lukas Preis, Dominik Lammerding, Daria Gref, Josef Priller, Eike J Spruth, Slawek Altenstein, Andrea Lohse, Stefan Hetzer, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Ina R Vogt, Jens Wiltfang, Claudia Bartels, Björn H Schott, Niels Hansen, Peter Dechent, Katharina Buerger, Daniel Janowitz, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H Munk, Carolin Sanzenbacher, Petra Hinderer, Klaus Scheffler, Annika Spottke, Nina Roy-Kluth, Falk Lüsebrink, Katja Neumann, Joanna Wardlaw, Frank Jessen, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler
Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study
Journal of the American Heart Association
Published
Choroid Plexus Volume in Rural Chinese Older Adults: Distribution and Association With Cardiovascular Risk Factors and Cerebral Small Vessel Disease
Authors
Chunyan Li, Huisi Zhang, Jiafeng Wang, Xiaodong Han, Cuicui Liu, Yuanjing Li, Tao Gong, Tingting Hou, Yongxiang Wang, Lin Cong, Grégoria Kalpouzos, Joanna Wardlaw, Lin Song, Yifeng Du, Chengxuan Qiu
Choroid Plexus Volume in Rural Chinese Older Adults: Distribution and Association With Cardiovascular Risk Factors and Cerebral Small Vessel Disease

Wardlaw lab

Explore the work of the Wardlaw lab focused on understanding how small vessel disease damages the brain and what we can do to prevent and treat it.

Superintendent Radiographer Charlotte Jardine and colleague examines brain scans on a computer screen