From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI.
Featured
- Research
Dementia is rare in midlife rugby players, but long-term risk may be increased
A study of 200 former professional rugby players (aged 30-61 years old), researchers from the UK DRI, Imperial College London and University College London (affiliated...
Sleep problems could double risk of dementia in later life
People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...
Alcohol consumption and cerebrospinal fluid biomarkers for preclinical alzheimer's disease in a population-based sample of 70-year-olds
Authors
Silke Kern, Tobias Skillbäck, Henrik Zetterberg, Anna Dittrich, Felicia Ahlner, Anna Zettergren, Margda Waern, Nazib M Seidu, Ulf Andreasson, Kaj Blennow, Ingmar Skoog
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review
Authors
Niti Sharma, Danyeong Kim, Himadri Sharma, Moon Il Kim, Hyon Lee, Minju Kim, Nayoung Ryoo, Min Ju Kang, Jung-Min Pyun, Young Ho Park, Jisun Ryu, Hyun Jung Oh, Hyun-Sik Yang, Hang-Rai Kim, Geon Ha Kim, Sangwon Han, YoungSoon Yang, Young Chul Youn, Charlotte Teunissen, Henrik Zetterberg, Philip Scheltens, Seong Soo A An, Young-Bum Kim, SangYun Kim, Alzheimer's Disease All Markers (ADAM) Research Group
Neurofilament, but not Alzheimer disease biomarkers in the acute phase correlate with cognitive performance after cardiac arrest
Authors
Johannes Lorentzson, Gisela Lilja, Erik Blennow Nordström, Kaj Blennow, Henrik Zetterberg, Christian Hassager, Matt P Wise, Andrea L Benedet, Tommaso Pellis, Hans Friberg, Nicholas Ashton, Marion Moseby Knappe
Pupil-linked arousal, cortical activity, and cognition in Alzheimer's disease
Authors
Michael C B David, Emma-Jane Mallas, Lucia M Li, Magdalena A Kolanko, Ramin Nilforooshan, Man Lai Tsoi, Hanim Karakoc, Karen Hoang, Johanna Brandt, Charikleia Triantafyllou, Dragos C Gruia, Darije Custovic, Peter J Lally, Karl A Zimmerman, Care Research and Technology Group of the UK Dementia Research Institute, Paresh A Malhotra, Gregory Scott, David J Sharp
Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI
Authors
Anna E Fürtjes, Isabelle F Foote, Charley Xia, Gail Davies, Joanna Moodie, Adele Taylor, David C Liewald, Paul Redmond, Janie Corley, Andrew M McIntosh, Heather C Whalley, Susana Muñoz Maniega, Maria Valdés Hernández, Ellen Backhouse, Karen Ferguson, Mark E Bastin, Joanna Wardlaw, Javier de la Fuente, Andrew D Grotzinger, Michelle Luciano, W David Hill, Ian J Deary, Elliot M Tucker-Drob, Simon R Cox
Identification of protein targets for dyslipidaemia and cardiovascular diseases among people with South Asian ancestry: a mendelian randomisation study
Authors
Siwei Wu, Devendra Meena, Alexander Smith, Jingxian Huang, Georg W Otto, Yi-Hsuan Ko, James Yarmolinsky, Dipender Gill, Anand Rohatgi, Abbas Dehghan, Ioanna Tzoulaki
Associations between life course exposure to ambient air pollution with cognition and later-life brain structure: a population-based study of the 1946 British Birth Cohort
Authors
Thomas Canning, Jorge Arias-de la Torre, Helen L Fisher, John Gulliver, Anna L Hansell, Rebecca Hardy, Stephani L Hatch, Ian S Mudway, Amy Ronaldson, Molly Cartlidge, Sarah-Naomi James, Sarah E Keuss, Jonathan M Schott, Marcus Richards, Ioannis Bakolis
European journal of nuclear medicine and molecular imaging
Published
Comparison of two preprocessing methods for <sup>18</sup>F-Flortaucipir PET quantification in Alzheimer's disease
Authors
Elif Harput, Debora Elisa Peretti, Max Scheffler, Nicholas J Ashton, Kaj Blennow, Henrik Zetterberg, Ruben Smith, Giovanni B Frisoni, Valentina Garibotto, Cecilia Boccalini
Associations between night/shift working and late-life brain health
Authors
Josh King-Robson, Jennifer M Nicholas, Sarah-Naomi James, Ashvini Keshavan, Dylan M Williams, James Groves, Carole H Sudre, Kirsty Lu, Josephine Barnes, William Coath, David M Cash, Sarah E Keuss, Marcus Richards, Jason D Warren, Jonathan M Schott