Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

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- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Nature communications
Published

CSF total tau as a proxy of synaptic degeneration

Authors
Carolina Soares, Bruna Bellaver, Pamela C L Ferreira, Guilherme Povala, Cristiano Schaffer Aguzzoli, João Pedro Ferrari-Souza, Hussein Zalzale, Firoza Z Lussier, Francieli Rohden, Sarah Abbas, Guilherme Bauer-Negrini, Douglas Teixeira Leffa, Andréa Lessa Benedet, Rebecca Langhough, Tobey J Betthauser, Bradley T Christian, Rachael E Wilson, Dana L Tudorascu, Pedro Rosa-Neto, Thomas K Karikari, Henrik Zetterberg, Kaj Blennow, Eduardo R Zimmer, Sterling C Johnson, Tharick A Pascoal
CSF total tau as a proxy of synaptic degeneration
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Associations between fluid biomarkers and PET imaging ([11C]UCB-J) of synaptic pathology in Alzheimer's disease

Authors
Johanna Nilsson, Adam P Mecca, Nicholas J Ashton, Elaheh Salardini, Ryan S O'Dell, Richard E Carson, Andrea L Benedet, Kaj Blennow, Henrik Zetterberg, Christopher H van Dyck, Ann Brinkmalm
Associations between fluid biomarkers and PET imaging ([11C]UCB-J) of synaptic pathology in Alzheimer's disease
Frontiers in veterinary science
Published

Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya

Authors
Sylvia Cheptoo, Erhan Yalcindag, Lina González Gordon, Benson Rukwaro, Joseph Samuel Kimatu, Joseph Wasonga, Benedict E Karani, Gideon Ndambuki, Susan Migeni, Jesse Kagai, Linus Eric Kiprotich, Nelson Saya, Deepali Vasoya, Getrude Nangekhe, Justus Onguso, Grace Mungai, Barend Mark Bronsvoort, Elizabeth Anne Jessie Cook
Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Alzheimer's disease traits in Parkinson's disease without α-synuclein seeding

Authors
Bárbara Fernandes Gomes, Carly M Farris, Yihua Ma, Luis Concha-Marambio, Johanna Nilsson, Karin Forsberg, Russ Lebovitz, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, David Bäckström
Alzheimer's disease traits in Parkinson's disease without α-synuclein seeding
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Published

The association of umbilical cord blood neurofilament light with non-reassuring fetal status: A prospective observational study

Authors
David Zalcberg, Kaitlin Kramer, Emma Payne, Thomas Payne, Shreeya Marathe, Neha Mahajan, Ashly Liu, Jessica Barry, Andrew Duckworth, Mitchell Brooks, Bradley de Vries, Fernando Gonzalez-Ortiz, Kaj Blennow, Henrik Zetterberg, Adrienne Gordon, Benjamin Moran, Helen J Manning, Robert D Sanders
The association of umbilical cord blood neurofilament light with non-reassuring fetal status: A prospective observational study
Science advances
Published

Gut-brain nexus: Mapping multimodal links to neurodegeneration at biobank scale

Authors
Mohammad Shafieinouri, Samantha Hong, Paul Suhwan Lee, Spencer M Grant, Marzieh Khani, Anant Dadu, Artur F Schumacher Schuh, Mary B Makarious, Rodrigo Sandon, Emily Simmonds, Hirotaka Iwaki, Gracelyn Hill, Cornelis Blauwendraat, Valentina Escott-Price, Yue A Qi, Alastair J Noyce, Armando Reyes-Palomares, Hampton L Leonard, Malu Tansey, Faraz Faghri, Andrew B Singleton, Mike A Nalls, Kristin S Levine, Sara Bandres-Ciga
Gut-brain nexus: Mapping multimodal links to neurodegeneration at biobank scale
Nature aging
Published

Plasma tau biomarkers for biological staging of Alzheimer's disease

Authors
Laia Montoliu-Gaya, Gemma Salvadó, Joseph Therriault, Johanna Nilsson, Shorena Janelidze, Sophia Weiner, Nicholas J Ashton, Andrea L Benedet, Nesrine Rahmouni, Juan Lantero-Rodriguez, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Gunnar Brinkmalm, Erik Stomrud, Henrik Zetterberg, Johan Gobom, Pedro Rosa-Neto, Kaj Blennow, Oskar Hansson
Plasma tau biomarkers for biological staging of Alzheimer's disease
Alzheimer's research & therapy
Published

The association between plasma and MRI biomarkers in dementia with lewy bodies

Authors
Carmen Peña-Bautista, Katharina Bolsewig, Maria C Gonzalez, Nicholas J Ashton, Dag Aarsland, Henrik Zetterberg, Eric Westman, Olivier Bousiges, Frederic Blanc, Charlotte E Teunissen, Afina W Lemstra, Consuelo Cháfer-Pericás, Miguel Baquero, Daniel Ferreira
The association between plasma and MRI biomarkers in dementia with lewy bodies
Brain stimulation
Published

Brief transcranial focused ultrasound stimulation causes lasting modifications to the synaptic circuitry of the hippocampus

Authors
William W Watts, Benjamin Clennell, James K Jiang, Konoha Izaki-Lee, Abhishek Binodh, Robyn Cuthell, Deniz Tonyali, Jon Crompton, Rosie Taaffe, Alanoud Alqahtani, Anna Andrieu, Igino Rafael Besinga, Kate Heesom, Tom G J Steward, Kwangwook Cho, Bruce W Drinkwater, Elek Molnár, Daniel J Whitcomb
Brief transcranial focused ultrasound stimulation causes lasting modifications to the synaptic circuitry of the hippocampus
Clinical chemistry and laboratory medicine
Published

Validation of a plasma GFAP immunoassay and establishment of age-related reference values: bridging analytical performance and routine implementation

Authors
Burak Arslan, Ulf Andreasson, Elzbieta Rembeza, Markus Axelsson, Lenka Novakova, Bjørn-Eivind Kirsebom, Tormod Fladby, Anna Dittrich, Silke Kern, Ingmar Skoog, Kaj Blennow, Henrik Zetterberg, Hlin Kvartsberg
Validation of a plasma GFAP immunoassay and establishment of age-related reference values: bridging analytical performance and routine implementation
Scientific reports
Published

Mapping Alzheimer's disease pathology using free water through integrated analysis of plasma biomarkers, microstructural DTI metrics, and macrostructural MRI measures

Authors
Bo-Hyun Kim, Daeun Shin, Sung Hoon Kang, Hyemin Jang, Jihwan Yun, YuHyun Park, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Sung Tae Kim, Hee Jin Kim, Duk L Na, Jun Pyo Kim, Sang Won Seo
Mapping Alzheimer's disease pathology using free water through integrated analysis of plasma biomarkers, microstructural DTI metrics, and macrostructural MRI measures