Skip to main content
Search
Main content

Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Synapse (New York, N.Y.)
Published

Synaptosomal-Associated Protein 25 kDA (SNAP-25) Levels in Cerebrospinal Fluid: Implications for Alzheimer's Disease Diagnosis and Monitoring

Authors
Sofia Hjorth Wolner, Helena Sophia Gleerup, Christian Sandøe Musaeus, Peter Høgh, Nicholas J Ashton, Ann Brinkmalm, Johanna Nilsson, Lana Grötschel, Henrik Zetterberg, Kaj Blennow, Steen Gregers Hasselbalch, Anne Byriel Walls, Anja Hviid Simonsen
Synaptosomal-Associated Protein 25 kDA (SNAP-25) Levels in Cerebrospinal Fluid: Implications for Alzheimer's Disease Diagnosis and Monitoring
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker-guided diagnostics

Authors
Hyemin Jang, Daeun Shin, Heejin Yoo, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Theresa A Day, Eun Hye Lee, Jihwan Yun, Duk L Na, Hee Jin Kim, Sung Hoon Kang, Ko Woon Kim, Si Eun Kim, Yeo Jin Kim, Yeshin Kim, Jaeho Kim, Chi-Hun Kim, Min Young Chun, Na Yeon Jung, Soo Hyun Cho, Jun Pyo Kim, Sang Won Seo, K‐ROAD study groups
Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker-guided diagnostics
Science translational medicine
Published

Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes

Authors
Aitana Sogorb-Esteve, Sophia Weiner, Joel Simrén, Imogen J Swift, Martina Bocchetta, Emily G Todd, David M Cash, Arabella Bouzigues, Lucy L Russell, Phoebe H Foster, Eve Ferry-Bolder, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tiraboschi, Isabel Santana, Alexander Gerhard, Johannes Levin, Sandro Sorbi, Markus Otto, Florence Pasquier, Simon Ducharme, Chris R Butler, Isabelle Le Ber, Elizabeth Finger, Maria Carmela Tartaglia, Mario Masellis, James B Rowe, Matthis Synofzik, Fermin Moreno, Barbara Borroni, None Genfi, Kaj Blennow, Henrik Zetterberg, Jonathan D Rohrer, Johan Gobom, GENFI
Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study

Authors
Nicholas J Ashton, Ashvini Keshavan, Wagner S Brum, Ulf Andreasson, Burak Arslan, Mathias Droescher, Stefan Barghorn, Jeroen Vanbrabant, Charlotte Lambrechts, Maxime Van Loo, Erik Stoops, Shweta Iyengar, HaYeun Ji, Xiaomei Xu, Alex Forrest-Hay, Bingqing Zhang, Yuling Luo, Andreas Jeromin, Manu Vandijck, Nathalie Le Bastard, Hartmuth Kolb, Gallen Triana-Baltzer, Divya Bali, Shorena Janelidze, Shieh-Yueh Yang, Catherine Demos, Daniel Romero, George Sigal, Jacob Wohlstadter, Kishore Malyavantham, Meenakshi Khare, Alexander Jethwa, Laura Stoeckl, Johan Gobom, Przemysław R Kac, Fernando Gonzalez-Ortiz, Laia Montoliu-Gaya, Oskar Hansson, Robert A Rissman, Maria C Carrillo, Leslie M Shaw, Kaj Blennow, Jonathan M Schott, Henrik Zetterberg
The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study
Brain : a journal of neurology
Published

The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset

Authors
Haiyan Liu, Thomas W Marsh, Xinyu Shi, Alan E Renton, Kevin M Bowling, Ellen Ziegemeier, Guoqiao Wang, Yuchen Cao, Alisha Aristel, Jessie Li, Alexa Dickson, Richard J Perrin, Alison M Goate, Victoria Fernández, Gregory S Day, Michelle Doering, Alisha Daniels, Brian A Gordon, Tammie L S Benzinger, Jason Hassenstab, Laura Ibanez, Charlene Supnet-Bell, Chengjie Xiong, Ricardo Allegri, Sarah B Berman, Nick C Fox, Natalie Ryan, Edward D Huey, Jonathan Vöglein, James M Noble, Jee Hoon Roh, Mathias Jucker, Christoph Laske, Takeshi Ikeuchi, Raquel Sanchez-Valle, Peter R Schofield, Patricio Chrem Mendez, Jasmeer P Chhatwal, Martin Farlow, Jae-Hong Lee, Allan I Levey, Johannes Levin, Francisco Lopera, Ralph Martins, Yoshiki Niimi, Pedro Rosa-Neto, John C Morris, Randall J Bateman, Celeste M Karch, Carlos Cruchaga, Eric McDade, Jorge J Llibre-Guerra
The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset
Neurology
Published

Longitudinal Cognitive Changes in Cerebral Small Vessel Disease: The Effect of White Matter Hyperintensity Regression and Progression

Authors
Angela C C Jochems, Susana Muñoz Maniega, Una Clancy, Carmen Arteaga-Reyes, Daniela Jaime Garcia, Francesca M Chappell, Olivia K L Hamilton, Ellen V Backhouse, Gayle Barclay, Charlotte Jardine, Donna McIntyre, Iona Hamilton, Eleni Sakka, Maria Del C Valdés Hernández, Stewart Wiseman, Mark E Bastin, Michael S Stringer, Michael Thrippleton, Fergus Doubal, Joanna M Wardlaw
Longitudinal Cognitive Changes in Cerebral Small Vessel Disease: The Effect of White Matter Hyperintensity Regression and Progression
EClinicalMedicine
Published

An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept study

Authors
Marirena Bafaloukou, Ann-Kathrin Schalkamp, Nan Fletcher-Lloyd, Alex Capstick, Chloe Walsh, Cynthia Sandor, Samaneh Kouchaki, CR&T Group, Ramin Nilforooshan, Payam Barnaghi
An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept study
Brain communications
Published

The relationship between leisure time physical activity patterns, Alzheimer's disease markers and cognition

Authors
Sarah-Naomi James, Carole H Sudre, Josephine Barnes, David M Cash, Yu-Jie Chiou, William Coath, Ashvini Keshavan, Kirsty Lu, Ian Malone, Heidi Murray-Smith, Jennifer M Nicholas, Michele Orini, Thomas Parker, Pamela Almeida-Meza, Nick C Fox, Marcus Richards, Jonathan M Schott
The relationship between leisure time physical activity patterns, Alzheimer's disease markers and cognition
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Soluble Aβ pathology predicts neurodegeneration and cognitive decline independently on p-tau in the earliest Alzheimer's continuum: Evidence across two independent cohorts

Authors
Raffaele Cacciaglia, Carles Falcón, Gonzalo Sánchez Benavides, Anna Brugulat-Serrat, Marta Milà Alomà, Marc Suárez Calvet, José Luis Molinuevo, Karine Fauria, Carolina Minguillón, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Kaj Blennow, Henrik Zetterberg, Luigi Lorenzini, Alle Meije Wink, Silvia Ingala, Frederik Barkhof, Craig W Ritchie, Juan Domingo Gispert, ALFA study
Soluble Aβ pathology predicts neurodegeneration and cognitive decline independently on p-tau in the earliest Alzheimer's continuum: Evidence across two independent cohorts