Skip to main content
Search
Main content

Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Current biology : CB
Published
A REM-active basal ganglia circuit that regulates anxiety
Authors
Wei Ba, Mathieu Nollet, Chunyu Yin, Xiao Yu, Sara Wong, Andawei Miao, Esteban J Beckwith, Edward C Harding, Ying Ma, Raquel Yustos, Alexei L Vyssotski, William Wisden, Nicholas P Franks
A REM-active basal ganglia circuit that regulates anxiety
Sci Adv
Published
The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1.
Authors
Emil K Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H Reynolds, James R Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H Douse, Anita Adami, Diahann A M Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W Wood, Henry Houlden, Harpreet Saini, Carla F Bento, John Hardy, Mina Ryten
The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1.
Communications medicine
Published
Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium
Authors
Mari Aksnes, Mari Haavig Schibstad, Farrukh Abbas Chaudhry, Bjørn Erik Neerland, Gideon Caplan, Ingvild Saltvedt, Rannveig S Eldholm, Marius Myrstad, Trine Holt Edwin, Karin Persson, Ane-Victoria Idland, Christian Thomas Pollmann, Roy Bjørkholt Olsen, Torgeir Bruun Wyller, Henrik Zetterberg, Emma Cunningham, Leiv Otto Watne
Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant pathologies
Authors
Andreja Emeršič, Nicholas J Ashton, Agathe Vrillon, Juan Lantero-Rodriguez, Jernej Mlakar, Milica Gregorič Kramberger, Fernando Gonzalez-Ortiz, Przemysław R Kac, Maciej Dulewicz, Jörg Hanrieder, Eugeen Vanmechelen, Uroš Rot, Henrik Zetterberg, Thomas K Karikari, Saša Čučnik, Kaj Blennow
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant pathologies
Science advances
Published
The annotation of <em>GBA1</em> has been concealed by its protein-coding pseudogene <em>GBAP1</em>
Authors
Emil K Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H Reynolds, James R Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H Douse, Anita Adami, Diahann A M Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W Wood, Henry Houlden, Harpreet Saini, Carla F Bento, John Hardy, Mina Ryten
The annotation of <em>GBA1</em> has been concealed by its protein-coding pseudogene <em>GBAP1</em>
NPJ Parkinson's disease
Published
Author Correction: Lysosomal and synaptic dysfunction markers in longitudinal cerebrospinal fluid of de novo Parkinson's disease
Authors
Michael Bartl, Johanna Nilsson, Mohammed Dakna, Sandrina Weber, Sebastian Schade, Mary Xylaki, Bárbara Fernandes Gomes, Marielle Ernst, Maria-Lucia Muntean, Friederike Sixel-Döring, Claudia Trenkwalder, Henrik Zetterberg, Ann Brinkmalm, Brit Mollenhauer
Author Correction: Lysosomal and synaptic dysfunction markers in longitudinal cerebrospinal fluid of de novo Parkinson's disease
BMJ open
Published
Protocol for a double-blind placebo-controlled randomised controlled trial assessing the impact of oral semaglutide in amyloid positivity (ISAP) in community dwelling UK adults
Authors
Ivan Koychev, Amanda I Adler, Paul Edison, Brian Tom, Joanne E Milton, Joe Butchart, Adam Hampshire, Charles Marshall, Elizabeth Coulthard, Henrik Zetterberg, Peter Hellyer, Francesca Cormack, Benjamin R Underwood, Catherine J Mummery, Rury R Holman
Protocol for a double-blind placebo-controlled randomised controlled trial assessing the impact of oral semaglutide in amyloid positivity (ISAP) in community dwelling UK adults
Cerebral cortex (New York, N.Y. : 1991)
Published
Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study
Authors
Elise Beckers, Maxime Van Egroo, Nicholas J Ashton, Kaj Blennow, Gilles Vandewalle, Henrik Zetterberg, Benedikt A Poser, Heidi I L Jacobs
Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study
Biology of sex differences
Published
Sex-specific differences in the mechanisms for enhanced thromboxane A<sub>2</sub>-mediated vasoconstriction in adult offspring exposed to prenatal hypoxia
Authors
Murilo E Graton, Floor Spaans, Rose He, Paulami Chatterjee, Raven Kirschenman, Anita Quon, Tom J Phillips, C Patrick Case, Sandra T Davidge
Sex-specific differences in the mechanisms for enhanced thromboxane A<sub>2</sub>-mediated vasoconstriction in adult offspring exposed to prenatal hypoxia
bioRxiv : the preprint server for biology
Published
The inactive X chromosome drives sex differences in microglial inflammatory activity in human glioblastoma
Authors
Marla E Tharp, Claudia Z Han, Chris D Balak, Conor Fitzpatrick, Carolyn O'Connor, Sebastian Preissl, Justin Buchanan, Alexi Nott, Laure Escoubet, Konstantinos Mavrommatis, Mihir Gupta, Marc S Schwartz, U Hoi Sang, Pamela S Jones, Michael L Levy, David D Gonda, Sharona Ben-Haim, Joseph Ciacci, David Barba, Alexander Khalessi, Nicole G Coufal, Clark C Chen, Christopher K Glass, David C Page
The inactive X chromosome drives sex differences in microglial inflammatory activity in human glioblastoma