Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Sci Adv
Published

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.

Authors
Nicol Birsa, Agnieszka M Ule, Maria Giovanna Garone, Brian Tsang, Francesca Mattedi, P Andrew Chong, Jack Humphrey, Seth Jarvis, Melis Pisiren, Oscar G Wilkins, Micheal L Nosella, Anny Devoy, Cristian Bodo, Rafaela Fernandez de la Fuente, Elizabeth M C Fisher, Alessandro Rosa, Gabriella Viero, Julie D Forman-Kay, Giampietro Schiavo, Pietro Fratta
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.
Sci Adv
Published

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.

Authors
Nicol Birsa, Agnieszka M Ule, Maria Giovanna Garone, Brian Tsang, Francesca Mattedi, P Andrew Chong, Jack Humphrey, Seth Jarvis, Melis Pisiren, Oscar G Wilkins, Micheal L Nosella, Anny Devoy, Cristian Bodo, Rafaela Fernandez de la Fuente, Elizabeth M C Fisher, Alessandro Rosa, Gabriella Viero, Julie D Forman-Kay, Giampietro Schiavo, Pietro Fratta
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.
J Neurol Neurosurg Psychiatry
Published

Neuroinflammation predicts disease progression in progressive supranuclear palsy.

Authors
Maura Malpetti, Luca Passamonti, Peter Simon Jones, Duncan Street, Timothy Rittman, Timothy D Fryer, Young T Hong, Patricia Vàsquez Rodriguez, William Richard Bevan-Jones, Franklin I Aigbirhio, John Tiernan O'Brien, James Benedict Rowe
Neuroinflammation predicts disease progression in progressive supranuclear palsy.
J Neurol Neurosurg Psychiatry
Published

Neuroinflammation predicts disease progression in progressive supranuclear palsy.

Authors
Maura Malpetti, Luca Passamonti, Peter Simon Jones, Duncan Street, Timothy Rittman, Timothy D Fryer, Young T Hong, Patricia Vàsquez Rodriguez, William Richard Bevan-Jones, Franklin I Aigbirhio, John Tiernan O'Brien, James Benedict Rowe
Neuroinflammation predicts disease progression in progressive supranuclear palsy.
Intensive Care Med
Published

Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom.

Authors
Brijesh V Patel, Shlomi Haar, Rhodri Handslip, Chaiyawan Auepanwiriyakul, Teresa Mei-Ling Lee, Sunil Patel, J Alex Harston, Feargus Hosking-Jervis, Donna Kelly, Barnaby Sanderson, Barbara Borgatta, Kate Tatham, Ingeborg Welters, Luigi Camporota, Anthony C Gordon, Matthieu Komorowski, David Antcliffe, John R Prowle, Zudin Puthucheary, Aldo A Faisal
Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom.