Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Brain communications
Published
Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury
Authors
Alex Tsui, Benjamin Johnstone, Amanda Heslegrave, Henrik Zetterberg, Leiv Otto Watne, Bjørn Erik Neerland, Maria Krogseth, Colm Cunningham, Alasdair MacLullich, Graciela Muniz Terrera, Daniel Davis, Gideon Caplan
Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players
Authors
Annalise E Miner, Jenna R Groh, Yorghos Tripodis, Charles H Adler, Laura J Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine Peskind, Nicholas J Ashton, Charles E Gaudet, Brett Martin, Joseph N Palmisano, Sarah J Banks, William B Barr, Jennifer V Wethe, Robert C Cantu, David W Dodick, Douglas I Katz, Jesse Mez, Suzan van Amerongen, Jeffrey L Cummings, Martha E Shenton, Eric M Reiman, Robert A Stern, Michael L Alosco, DIAGNOSE CTE Research Project
Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players
Nature medicine
Published
Increased frequency of repeat expansion mutations across different populations
Authors
Kristina Ibañez, Bharati Jadhav, Matteo Zanovello, Delia Gagliardi, Christopher Clarkson, Stefano Facchini, Paras Garg, Alejandro Martin-Trujillo, Scott J Gies, Valentina Galassi Deforie, Anupriya Dalmia, Davina J Hensman Moss, Jana Vandrovcova, Clarissa Rocca, Loukas Moutsianas, Chiara Marini-Bettolo, Helen Walker, Chris Turner, Maryam Shoai, Jeffrey D Long, Pietro Fratta, Douglas R Langbehn, Sarah J Tabrizi, Mark J Caulfield, Andrea Cortese, Valentina Escott-Price, John Hardy, Henry Houlden, Andrew J Sharp, Arianna Tucci
Increased frequency of repeat expansion mutations across different populations
EClinicalMedicine
Published
Changes in memory and cognition during the SARS-CoV-2 human challenge study.
Authors
William Trender, Peter J Hellyer, Ben Killingley, Mariya Kalinova, Alex J Mann, Andrew P Catchpole, David Menon, Edward Needham, Ryan Thwaites, Christopher Chiu, Gregory Scott, Adam Hampshire
Changes in memory and cognition during the SARS-CoV-2 human challenge study.
Nat Med
Published
Increased frequency of repeat expansion mutations across different populations.
Authors
Kristina Ibañez, Bharati Jadhav, Matteo Zanovello, Delia Gagliardi, Christopher Clarkson, Stefano Facchini, Paras Garg, Alejandro Martin-Trujillo, Scott J Gies, Valentina Galassi Deforie, Anupriya Dalmia, Davina J Hensman Moss, Jana Vandrovcova, Clarissa Rocca, Loukas Moutsianas, Chiara Marini-Bettolo, Helen Walker, Chris Turner, Maryam Shoai, Jeffrey D Long, Pietro Fratta, Douglas R Langbehn, Sarah J Tabrizi, Mark J Caulfield, Andrea Cortese, Valentina Escott-Price, John Hardy, Henry Houlden, Andrew J Sharp, Arianna Tucci
Increased frequency of repeat expansion mutations across different populations.
BMC geriatrics
Published
Experiences with home monitoring technology in older adults with traumatic brain injury: a qualitative study
Authors
Megan E Parkinson, Rebecca M Smith, Karen Tanious, Francesca Curtis, Rebecca Doherty, Lorena Colon, Lucero Chena, Sophie C Horrocks, Matthew Harrison, Michael B Fertleman, Melanie Dani, Payam Barnaghi, David J Sharp, UK Dementia Research Institute Care Research & Technology Research Group, Lucia M Li
Experiences with home monitoring technology in older adults with traumatic brain injury: a qualitative study
Nature communications
Published
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Authors
Susan Kilgas, Aleem Syed, Patrick Toolan-Kerr, Michelle L Swift, Shrabasti Roychoudhury, Aniruddha Sarkar, Sarah Wilkins, Mikayla Quigley, Anna R Poetsch, Maria Victoria Botuyan, Gaofeng Cui, Georges Mer, Jernej Ule, Pascal Drané, Dipanjan Chowdhury
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Practical neurology
Published
Repeat expansion disorders
Authors
Zhongbo Chen, Huw R Morris, James Polke, Nicholas W Wood, Sonia Gandhi, Mina Ryten, Henry Houlden, Arianna Tucci
Repeat expansion disorders
Nat Neurosci
Published
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice.
Authors
Damien Levard, Célia Seillier, Mathys Bellemain-Sagnard, Antoine Philippe Fournier, Eloïse Lemarchand, Chantal Dembech, Gaëtan Riou, Karina McDade, Colin Smith, Conor McQuaid, Axel Montagne, Lukas Amann, Marco Prinz, Denis Vivien, Marina Rubio
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice.
iScience
Published
Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19
Authors
Marina O Rontogianni, Dipender Gill, Emmanouil Bouras, Alexandros-Georgios Asimakopoulos, Ioanna Tzoulaki, Ville Karhunen, Terho Lehtimäki, Olli Raitakari, Matthias Wielscher, Veikko Salomaa, Sirpa Jalkanen, Marko Salmi, Markku Timonen, James Yarmolinsky, Jing Chen, Martin D Tobin, Abril G Izquierdo, Karl-Heinz Herzig, Anne E Ioannides, Marjo-Riitta Jarvelin, Abbas Dehghan, Konstantinos K Tsilidis
Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19