Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

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- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Brain Communications
Published

Predictive blood biomarkers and brain changes associated with age-related cognitive decline

Authors
Tyler S Saunders, Francesca E Pozzolo, Amanda Heslegrave, Declan King, Robert I. McGeachan, Maxwell P Spires-Jones, Sarah E Harris, Craig Ritchie, Graciela Muniz-Terrera, Ian J Deary, Simon R Cox, Henrik Zetterberg, Tara L. Spires-Jones
Predictive blood biomarkers and brain changes associated with age-related cognitive decline
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Published

COVID-19 and stroke in women: impact on clinical, psychosocial and research aspects

Authors
Isabella Canavero, Benedetta Storti, Giulia Marinoni, Diana Aguiar De Souza, Elena Moro, Laura Gatti, Simona Sacco, Svetlana Lorenzano, Else C Sandset, Anna Poggesi, Tatiana Carrozzini, Giuliana Pollaci, Antonella Potenza, Gemma Gorla, Joanna M Wardlaw, Maria Luisa Zedde, Anna Bersano
COVID-19 and stroke in women: impact on clinical, psychosocial and research aspects
Frontiers in neuroscience
Published

Methodological challenges of measuring brain volumes and cortical thickness in idiopathic normal pressure hydrocephalus with a surface-based approach

Authors
Martina Del Giovane, Michael C B David, Magdalena A Kolanko, Anastasia Gontsarova, Thomas Parker, Adam Hampshire, David J Sharp, Paresh A Malhotra, Christopher Carswell
Methodological challenges of measuring brain volumes and cortical thickness in idiopathic normal pressure hydrocephalus with a surface-based approach
Curr Biol
Published

A REM-active basal ganglia circuit that regulates anxiety.

Authors
Wei Ba, Mathieu Nollet, Chunyu Yin, Xiao Yu, Sara Wong, Andawei Miao, Esteban J Beckwith, Edward C Harding, Ying Ma, Raquel Yustos, Alexei L Vyssotski, William Wisden, Nicholas P Franks
A REM-active basal ganglia circuit that regulates anxiety.
Trials
Published

Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event

Authors
Mia S Tackney, Amber Steele, Joseph Newman, Marie-Christine Fritzsche, Federica Lucivero, Zarnie Khadjesari, Jennifer Lynch, Rosemary A Abbott, Vicki S Barber, James R Carpenter, Bethan Copsey, Elin H Davies, William G Dixon, Lisa Fox, Javier González, Jessica Griffiths, Chloe H L Hinchliffe, Magdalena A Kolanko, Dylan McGagh, Aryelly Rodriguez, George Roussos, Karen B E So, Louise Stanton, Mark Toshner, Frances Varian, Paula R Williamson, Belay B Yimer, Sofía S Villar
Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event
Neuron
Published

Synaptic oligomeric tau in Alzheimer’s disease - A potential culprit in the spread of tau pathology through the brain.

Authors
Martí Colom-Cadena, Caitlin Davies , Sònia Sirisi, Ji-Eun Lee, Elizabeth M. Simzer, Makis Tzioras, Marta Querol-Vilaseca, Érika Sánchez-Aced, Ya Yin Chang, Kristjan Holt, Robert I. McGeachan, Jamie Rose, Jane Tulloch, Lewis Wilkins, Colin Smith, Teodora Andrian, Olivia Belbin, Sílvia Pujals, Mathew H. Horrocks, Alberto Lleó, Tara L. Spires-Jones
Synaptic oligomeric tau in Alzheimer’s disease - A potential culprit in the spread of tau pathology through the brain.
Molecular cell
Published

The V-ATPase/ATG16L1 axis is controlled by the V<sub>1</sub>H subunit

Authors
Lewis Timimi, Antoni G Wrobel, George N Chiduza, Sarah L Maslen, Antonio Torres-Méndez, Beatriz Montaner, Colin Davis, Taylor Minckley, Katriona L Hole, Andrea Serio, Michael J Devine, J Mark Skehel, John L Rubinstein, Anne Schreiber, Rupert Beale
The V-ATPase/ATG16L1 axis is controlled by the V<sub>1</sub>H subunit
The EMBO journal
Published

Author Correction: Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models

Authors
Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natália Jurčáková, Gerard Crowley, Sebastiaan De Schepper, Judy Z Ge, Joanne I Lachica, Christina E Toomey, Oliver J Freeman, John Hardy, Samuel J Barnes, Tammaryn Lashley, Beth Stevens, Sunghoe Chang, Soyon Hong
Author Correction: Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Osteopontin: A novel marker of pre-symptomatic sporadic Alzheimer's disease

Authors
Marc James Quesnel, Anne Labonté, Cynthia Picard, Daniel C Bowie, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm, Sylvia Villeneuve, Judes Poirier, Alzheimer's Disease Neuroimaging Initiative, PREVENT‐AD Research Group
Osteopontin: A novel marker of pre-symptomatic sporadic Alzheimer's disease
Cortex; a journal devoted to the study of the nervous system and behavior
Published

Examining the neurostructural architecture of intelligence: The Lothian Birth Cohort 1936 study

Authors
Danielle Page, Colin R Buchanan, Joanna E Moodie, Mathew A Harris, Adele Taylor, Maria Valdés Hernández, Susana Muñoz Maniega, Janie Corley, Mark E Bastin, Joanna M Wardlaw, Tom C Russ, Ian J Deary, Simon R Cox
Examining the neurostructural architecture of intelligence: The Lothian Birth Cohort 1936 study