Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

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- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Eur Stroke J
Published

ESO Guideline on covert cerebral small vessel disease.

Authors
Joanna M Wardlaw, Stephanie Debette, Hanna Jokinen, Frank-Erik De Leeuw, Leonardo Pantoni, Hugues Chabriat, Julie Staals, Fergus Doubal, Salvatore Rudilosso, Sebastian Eppinger, Sabrina Schilling, Raffaele Ornello, Christian Enzinger, Charlotte Cordonnier, Martin Taylor-Rowan, Arne G Lindgren
ESO Guideline on covert cerebral small vessel disease.
Cell Calcium
Published

Multi-scale network imaging in a mouse model of amyloidosis.

Authors
Nazanin Doostdar, Joseph Airey, Carola I Radulescu, Leire Melgosa-Ecenarro, Nawal Zabouri, Pavlina Pavlidi, Maksym Kopanitsa, Takashi Saito, Takaomi Saido, Samuel J Barnes
Multi-scale network imaging in a mouse model of amyloidosis.
J Cell Biol
Published

FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.

Authors
Brunno R Levone, Silvia C Lenzken, Marco Antonaci, Andreas Maiser, Alexander Rapp, Francesca Conte, Stefan Reber, Jonas Mechtersheimer, Antonella E Ronchi, Oliver Mühlemann, Heinrich Leonhardt, M Cristina Cardoso, Marc-David Ruepp, Silvia M L Barabino
FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.
Alzheimers Res Ther
Published

Investigating the relationship between BMI across adulthood and late life brain pathologies.

Authors
Christopher A Lane, Josephine Barnes, Jennifer M Nicholas, John W Baker, Carole H Sudre, David M Cash, Thomas D Parker, Ian B Malone, Kirsty Lu, Sarah-Naomi James, Ashvini Keshavan, Sarah Buchanan, Sarah Keuss, Heidi Murray-Smith, Andrew Wong, Elizabeth Gordon, William Coath, Marc Modat, David Thomas, Rebecca Hardy, Marcus Richards, Nick C Fox, Jonathan M Schott
Investigating the relationship between BMI across adulthood and late life brain pathologies.
Curr Biol
Published

Astrocytes.

Authors
Philip Hasel, Shane A Liddelow
Astrocytes.
Sci Adv
Published

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.

Authors
Laura Fumagalli, Florence L Young, Steven Boeynaems, Mathias De Decker, Arpan R Mehta, Ann Swijsen, Raheem Fazal, Wenting Guo, Matthieu Moisse, Jimmy Beckers, Lieselot Dedeene, Bhuvaneish T Selvaraj, Tijs Vandoorne, Vanesa Madan, Marka van Blitterswijk, Denitza Raitcheva, Alexander McCampbell, Koen Poesen, Aaron D Gitler, Philipp Koch, Pieter Vanden Berghe, Dietmar Rudolf Thal, Catherine Verfaillie, Siddharthan Chandran, Ludo Van Den Bosch, Simon L Bullock, Philip Van Damme
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.
Nat Struct Mol Biol
Published

Target-induced clustering activates Trim-Away of pathogens and proteins.

Authors
Jingwei Zeng, Ana Filipa Santos, Aamir S Mukadam, Mariana Osswald, David A Jacques, Claire F Dickson, Stephen H McLaughlin, Christopher M Johnson, Leo Kiss, Jakub Luptak, Nadine Renner, Marina Vaysburd, William A McEwan, Eurico Morais-de-Sá, Dean Clift, Leo C James
Target-induced clustering activates Trim-Away of pathogens and proteins.