Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
JMIR Mhealth Uhealth
Published
Three Contactless Sleep Technologies Compared With Actigraphy and Polysomnography in a Heterogeneous Group of Older Men and Women in a Model of Mild Sleep Disturbance: Sleep Laboratory Study.
Authors
Kiran K G Ravindran, Ciro Della Monica, Giuseppe Atzori, Damion Lambert, Hana Hassanin, Victoria Revell, Derk-Jan Dijk
Three Contactless Sleep Technologies Compared With Actigraphy and Polysomnography in a Heterogeneous Group of Older Men and Women in a Model of Mild Sleep Disturbance: Sleep Laboratory Study.
Cereb Circ Cogn Behav
Published
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.
Authors
Sarmi Sri, Adam Greenstein, Alessandra Granata, Alex Collcutt, Angela C C Jochems, Barry W McColl, Blanca Díaz Castro, Caleb Webber, Carmen Arteaga Reyes, Catherine Hall, Catherine B Lawrence, Cheryl Hawkes, Chrysia-Maria Pegasiou-Davies, Claire Gibson, Colin L Crawford, Colin Smith, Denis Vivien, Fiona H McLean, Frances Wiseman, Gaia Brezzo, Giovanna Lalli, Harry A T Pritchard, Hugh S Markus, Isabel Bravo-Ferrer, Jade Taylor, James Leiper, Jason Berwick, Jian Gan, John Gallacher, Jonathan Moss, Jozien Goense, Letitia McMullan, Lorraine Work, Lowri Evans, Michael S Stringer, Mlj Ashford, Mohamed Abulfadl, Nina Conlon, Paresh Malhotra, Philip Bath, Rebecca Canter, Rosalind Brown, Selvi Ince, Silvia Anderle, Simon Young, Sophie Quick, Stefan Szymkowiak, Steve Hill, Stuart Allan, Tao Wang, Terry Quinn, Tessa Procter, Tracy D Farr, Xiangjun Zhao, Zhiyuan Yang, Atticus H Hainsworth, Joanna M Wardlaw
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.
EMBO J
Published
Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Authors
Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natália Jurčáková, Gerard Crowley, Sebastiaan De Schepper, Judy Z Ge, Joanne I Lachica, Christina E Toomey, Oliver J Freeman, John Hardy, Samuel J Barnes, Tammaryn Lashley, Beth Stevens, Sunghoe Chang, Soyon Hong
Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
EMBO J
Published
Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Authors
Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natália Jurčáková, Gerard Crowley, Sebastiaan De Schepper, Judy Z Ge, Joanne I Lachica, Christina E Toomey, Oliver J Freeman, John Hardy, Samuel J Barnes, Tammaryn Lashley, Beth Stevens, Sunghoe Chang, Soyon Hong
Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Cell Reports Medicine
Published
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8
Authors
Makis Tzioras, Michael J.D. Daniels, Caitlin Davies, Paul Baxter, Declan King, Sean McKay, Balazs Varga, Karla Popovic, Madison Hernandez, Anna J. Stevenson, Jack Barrington, Elizabeth Drinkwater, Julia Borella, Rebecca K. Holloway, Jane Tulloch, Jonathan Moss, Clare Latta, Jothy Kandasamy, Drahoslav Sokol, Colin Smith, Veronique E. Miron, Ragnhildur Thóra Káradóttir, Giles E. Hardingham, Christopher M. Henstridge, Paul M. Brennan, Barry W. McColl, Tara L. Spires-Jones
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8
Cell Rep Med
Published
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
Authors
Makis Tzioras, Michael J D Daniels, Caitlin Davies, Paul Baxter, Declan King, Sean McKay, Balazs Varga, Karla Popovic, Madison Hernandez, Anna J Stevenson, Jack Barrington, Elizabeth Drinkwater, Julia Borella, Rebecca K Holloway, Jane Tulloch, Jonathan Moss, Clare Latta, Jothy Kandasamy, Drahoslav Sokol, Colin Smith, Veronique E Miron, Ragnhildur Thóra Káradóttir, Giles E Hardingham, Christopher M Henstridge, Paul M Brennan, Barry W McColl, Tara L Spires-Jones
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
PLoS One
Published
A systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain.
Authors
Xue Ying Zhang, Marta Diaz-delCastillo, Lingsi Kong, Natasha Daniels, William MacIntosh-Smith, Aya Abdallah, Dominik Domanski, Denis Sofrenovic, Tsz Pui Skel Yeung, Diego Valiente, Jan Vollert, Emily Sena, Andrew S Rice, Nadia Soliman
A systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain.
Sci Data
Published
TIHM: An open dataset for remote healthcare monitoring in dementia.
Authors
Francesca Palermo, Yu Chen, Alexander Capstick, Nan Fletcher-Loyd, Chloe Walsh, Samaneh Kouchaki, Jessica True, Olga Balazikova, Eyal Soreq, Gregory Scott, Helen Rostill, Ramin Nilforooshan, Payam Barnaghi
TIHM: An open dataset for remote healthcare monitoring in dementia.
Sci Data
Published
TIHM: An open dataset for remote healthcare monitoring in dementia.
Authors
Francesca Palermo, Yu Chen, Alexander Capstick, Nan Fletcher-Loyd, Chloe Walsh, Samaneh Kouchaki, Jessica True, Olga Balazikova, Eyal Soreq, Gregory Scott, Helen Rostill, Ramin Nilforooshan, Payam Barnaghi
TIHM: An open dataset for remote healthcare monitoring in dementia.