Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Reproduction
Published
Unilateral lesion of the suprachiasmatic nucleus impairs estradiol feedback, follicular development, estrous cycle and ovulation.
Authors
Carlos-Camilo Silva, Diana Pamela Benítez, Angélica Flores, Georgina Daniela Cortés, Elizabeth Vieyra, Cinthia Rocío Juárez-Tapia, Jessica Romero-Reyes, Roberto Domínguez, Diana P Benitez, Shenyi Jiang, Jack Wood, Rui Wang, Chloe M Hall, Carlijn Peerboom, Natalie Wong, Katie M Stringer, Karina S Vitanova, Victoria C Smith, Dhaval Joshi, Takashi Saito, Takaomi C Saido, John Hardy, Jörg Hanrieder, Bart De Strooper, Dervis A Salih, Takshashila Tripathi, Frances A Edwards, Damian M Cummings, Karina S Vitanova, Katie M Stringer, Diana P Benitez, Jonathan Brenton, Damian M Cummings
Unilateral lesion of the suprachiasmatic nucleus impairs estradiol feedback, follicular development, estrous cycle and ovulation.
bioRxiv
Published
Creation of de novo cryptic splicing for ALS/FTD precision medicine.
Authors
Oscar G Wilkins, Max Z Y J Chien, Josette J Wlaschin, Maria Pisliakova, David Thompson, Holly Digby, Rebecca L Simkin, Juan Antinao Diaz, Puja R Mehta, Matthew J Keuss, Matteo Zanovello, Anna-Leigh Brown, Peter Harley, Annalucia Darbey, Rajvinder Karda, Elizabeth M C Fisher, Tom J Cunningham, Claire E Le Pichon, Jernej Ule, Pietro Fratta
Creation of de novo cryptic splicing for ALS/FTD precision medicine.
bioRxiv
Published
Creation of de novo cryptic splicing for ALS/FTD precision medicine.
Authors
Oscar G Wilkins, Max Z Y J Chien, Josette J Wlaschin, Maria Pisliakova, David Thompson, Holly Digby, Rebecca L Simkin, Juan Antinao Diaz, Puja R Mehta, Matthew J Keuss, Matteo Zanovello, Anna-Leigh Brown, Peter Harley, Annalucia Darbey, Rajvinder Karda, Elizabeth M C Fisher, Tom J Cunningham, Claire E Le Pichon, Jernej Ule, Pietro Fratta
Creation of de novo cryptic splicing for ALS/FTD precision medicine.
Nat Commun
Published
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Authors
Tracy-Shi Zhang Fang, Yu Sun, Andrew C Pearce, Simona Eleuteri, Mark Kemp, Christopher A Luckhurst, Rachel Williams, Ross Mills, Sarah Almond, Laura Burzynski, Nóra M Márkus, Christopher J Lelliott, Natasha A Karp, David J Adams, Stephen P Jackson, Jin-Feng Zhao, Ian G Ganley, Paul W Thompson, Gabriel Balmus, David K Simon
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Nat Commun
Published
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Authors
Tracy-Shi Zhang Fang, Yu Sun, Andrew C Pearce, Simona Eleuteri, Mark Kemp, Christopher A Luckhurst, Rachel Williams, Ross Mills, Sarah Almond, Laura Burzynski, Nóra M Márkus, Christopher J Lelliott, Natasha A Karp, David J Adams, Stephen P Jackson, Jin-Feng Zhao, Ian G Ganley, Paul W Thompson, Gabriel Balmus, David K Simon
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Nat Neurosci
Published
Non-invasive temporal interference electrical stimulation of the human hippocampus.
Authors
Ines R Violante, Ketevan Alania, Antonino M Cassarà, Esra Neufeld, Emma Acerbo, Romain Carron, Adam Williamson, Danielle L Kurtin, Edward Rhodes, Adam Hampshire, Niels Kuster, Edward S Boyden, Alvaro Pascual-Leone, Nir Grossman
Non-invasive temporal interference electrical stimulation of the human hippocampus.
Lancet Neurol
Published
Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
Authors
Anna Kopczak, Michael S Stringer, Hilde van den Brink, Danielle Kerkhofs, Gordon W Blair, Maud van Dinther, Carmen Arteaga Reyes, Daniela Jaime Garcia, Laurien Onkenhout, Karolina A Wartolowska, Michael J Thrippleton, Agniete Kampaite, Marco Duering, Julie Staals, Saskia Lesnik-Oberstein, Keith W Muir, Martin Middeke, Bo Norrving, Marie-Germaine Bousser, Ulrich Mansmann, Peter M Rothwell, Fergus N Doubal, Robert van Oostenbrugge, Geert Jan Biessels, Alastair J S Webb, Joanna M Wardlaw, Martin Dichgans
Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
JMIR Mhealth Uhealth
Published
Three Contactless Sleep Technologies Compared With Actigraphy and Polysomnography in a Heterogeneous Group of Older Men and Women in a Model of Mild Sleep Disturbance: Sleep Laboratory Study.
Authors
Kiran K G Ravindran, Ciro Della Monica, Giuseppe Atzori, Damion Lambert, Hana Hassanin, Victoria Revell, Derk-Jan Dijk
Three Contactless Sleep Technologies Compared With Actigraphy and Polysomnography in a Heterogeneous Group of Older Men and Women in a Model of Mild Sleep Disturbance: Sleep Laboratory Study.