Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI.

Featured

Engulfing cell

Jan 28, 2026 - Research

Targeting the gut's immune system could tackle early stages of Parkinson's

New research, led by Dr Soyon Hong and Dr Tim Bartels at the UK DRI at UCL, has revealed how Parkinson’s spreads from the gut...

Learn more Targeting the gut's immune system could tackle early stages of Parkinson's

Cytokines released by T cells after encountering cancer cells

Jan 23, 2026

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system

Jan 14, 2026 - Research

Brain shrinkage and inflammation predict disease progression in progressive supranuclear palsy

New research led by Dr Maura Malpetti and Noah Shapiro (UK DRI at Cambridge) reveals signs of brain shrinkage, inflammation and blood markers for nerve...

Learn more Brain shrinkage and inflammation predict disease progression in progressive supranuclear palsy

J Neurol Neurosurg Psychiatry

Published Jul 03, 2021

Neuroinflammation predicts disease progression in progressive supranuclear palsy.

Authors

Maura Malpetti, Luca Passamonti, Peter Simon Jones, Duncan Street, Timothy Rittman, Timothy D Fryer, Young T Hong, Patricia Vàsquez Rodriguez, William Richard Bevan-Jones, Franklin I Aigbirhio, John Tiernan O'Brien, James Benedict Rowe

Neuroinflammation predicts disease progression in progressive supranuclear palsy.

Physiol Rev

Published Jul 01, 2021

Do hippocampal pyramidal cells respond to nonspatial stimuli?

Authors

John O'Keefe, Julija Krupic

Do hippocampal pyramidal cells respond to nonspatial stimuli?

Physiol Rev

Published Jul 01, 2021

Do hippocampal pyramidal cells respond to nonspatial stimuli?

Authors

John O'Keefe, Julija Krupic

Do hippocampal pyramidal cells respond to nonspatial stimuli?

IEEE Trans Neural Syst Rehabil Eng

Published Jun 30, 2021

Quantification of Motor Function Post-Stroke Using Novel Combination of Wearable Inertial and Mechanomyographic Sensors.

Authors

Lewis Formstone, Weiguang Huo, Samuel Wilson, Alison McGregor, Paul Bentley, Ravi Vaidyanathan

Quantification of Motor Function Post-Stroke Using Novel Combination of Wearable Inertial and Mechanomyographic Sensors.

IEEE Trans Neural Syst Rehabil Eng

Published Jun 30, 2021

Transfer Learning for Clinical Sleep Pose Detection Using a Single 2D IR Camera.

Authors

Sara Mahvash Mohammadi, Shirin Enshaeifar, Adrian Hilton, Derk-Jan Dijk, Kevin Wells

Transfer Learning for Clinical Sleep Pose Detection Using a Single 2D IR Camera.

IEEE Trans Neural Syst Rehabil Eng

Published Jun 30, 2021

Quantification of Motor Function Post-Stroke Using Novel Combination of Wearable Inertial and Mechanomyographic Sensors.

Authors

Lewis Formstone, Weiguang Huo, Samuel Wilson, Alison McGregor, Paul Bentley, Ravi Vaidyanathan

Quantification of Motor Function Post-Stroke Using Novel Combination of Wearable Inertial and Mechanomyographic Sensors.

IEEE Trans Neural Syst Rehabil Eng

Published Jun 29, 2021

Wearable MMG-Plus-One Armband: Evaluation of Normal Force on Mechanomyography (MMG) to Enhance Human-Machine Interfacing.

Authors

C Sebastian Mancero Castillo, Samuel Wilson, Ravi Vaidyanathan, S Farokh Atashzar

Wearable MMG-Plus-One Armband: Evaluation of Normal Force on Mechanomyography (MMG) to Enhance Human-Machine Interfacing.

IEEE Trans Neural Syst Rehabil Eng

Published Jun 29, 2021

Wearable MMG-Plus-One Armband: Evaluation of Normal Force on Mechanomyography (MMG) to Enhance Human-Machine Interfacing.

Authors

C Sebastian Mancero Castillo, Samuel Wilson, Ravi Vaidyanathan, S Farokh Atashzar

Wearable MMG-Plus-One Armband: Evaluation of Normal Force on Mechanomyography (MMG) to Enhance Human-Machine Interfacing.

Curr Biol

Published Jun 07, 2021

Learning and memory: Scaling new areas.

Authors

Carola I Radulescu, Samuel J Barnes

Learning and memory: Scaling new areas.

Nat Commun

Published May 27, 2021

Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences.

Authors

K Shaw, L Bell, K Boyd, D M Grijseels, D Clarke, O Bonnar, H S Crombag, C N Hall

Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences.

Intensive Care Med

Published May 27, 2021

Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom.

Authors

Brijesh V Patel, Shlomi Haar, Rhodri Handslip, Chaiyawan Auepanwiriyakul, Teresa Mei-Ling Lee, Sunil Patel, J Alex Harston, Feargus Hosking-Jervis, Donna Kelly, Barnaby Sanderson, Barbara Borgatta, Kate Tatham, Ingeborg Welters, Luigi Camporota, Anthony C Gordon, Matthieu Komorowski, David Antcliffe, John R Prowle, Zudin Puthucheary, Aldo A Faisal

Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom.

Sci Transl Med

Published May 26, 2021

PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain.

Authors

Ari W Schaler, Avery M Runyan, Catherine L Clelland, Eric J Sydney, Stephanie L Fowler, Helen Y Figueroa, Seiji Shioda, Ismael Santa-Maria, Karen E Duff, Natura Myeku

PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain.

Mol Neurobiol

Published May 18, 2021

Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q.

Authors

Robert A J Byrne, Megan Torvell, Nikoleta Daskoulidou, Dina Fathalla, Eirini Kokkali, Sarah M Carpanini, B Paul Morgan

Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q.

Eur Stroke J

Published May 11, 2021

ESO Guideline on covert cerebral small vessel disease.

Authors

Joanna M Wardlaw, Stephanie Debette, Hanna Jokinen, Frank-Erik De Leeuw, Leonardo Pantoni, Hugues Chabriat, Julie Staals, Fergus Doubal, Salvatore Rudilosso, Sebastian Eppinger, Sabrina Schilling, Raffaele Ornello, Christian Enzinger, Charlotte Cordonnier, Martin Taylor-Rowan, Arne G Lindgren

ESO Guideline on covert cerebral small vessel disease.

Neurology

Published May 11, 2021

Timing and Impact of Psychiatric, Cognitive, and Motor Abnormalities in Huntington Disease.

Authors

Branduff McAllister, James F Gusella, G Bernhard Landwehrmeyer, Jong-Min Lee, Marcy E MacDonald, Michael Orth, Anne E Rosser, Nigel M Williams, Peter Holmans, Lesley Jones, Thomas H Massey,

Timing and Impact of Psychiatric, Cognitive, and Motor Abnormalities in Huntington Disease.

Cell Calcium

Published May 07, 2021

Multi-scale network imaging in a mouse model of amyloidosis.

Authors

Nazanin Doostdar, Joseph Airey, Carola I Radulescu, Leire Melgosa-Ecenarro, Nawal Zabouri, Pavlina Pavlidi, Maksym Kopanitsa, Takashi Saito, Takaomi Saido, Samuel J Barnes

Multi-scale network imaging in a mouse model of amyloidosis.

J Cell Biol

Published May 03, 2021

FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.

Authors

Brunno R Levone, Silvia C Lenzken, Marco Antonaci, Andreas Maiser, Alexander Rapp, Francesca Conte, Stefan Reber, Jonas Mechtersheimer, Antonella E Ronchi, Oliver Mühlemann, Heinrich Leonhardt, M Cristina Cardoso, Marc-David Ruepp, Silvia M L Barabino

FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.

J Cell Biol

Published May 03, 2021

FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.

Authors

Brunno R Levone, Silvia C Lenzken, Marco Antonaci, Andreas Maiser, Alexander Rapp, Francesca Conte, Stefan Reber, Jonas Mechtersheimer, Antonella E Ronchi, Oliver Mühlemann, Heinrich Leonhardt, M Cristina Cardoso, Marc-David Ruepp, Silvia M L Barabino

FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.