Publications

Featured

Jan 28, 2026 - Research

Targeting the gut's immune system could tackle early stages of Parkinson's

New research, led by Dr Soyon Hong and Dr Tim Bartels at the UK DRI at UCL, has revealed how Parkinson’s spreads from the gut...

Learn more Targeting the gut's immune system could tackle early stages of Parkinson's

Cytokines released by T cells after encountering cancer cells

Jan 23, 2026

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system

Jan 14, 2026 - Research

Brain shrinkage and inflammation predict disease progression in progressive supranuclear palsy

New research led by Dr Maura Malpetti and Noah Shapiro (UK DRI at Cambridge) reveals signs of brain shrinkage, inflammation and blood markers for nerve...

Learn more Brain shrinkage and inflammation predict disease progression in progressive supranuclear palsy

BMC Biol

Published Jan 10, 2015

Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum.

Authors

Edward Avezov, Tasuku Konno, Alisa Zyryanova, Weiyue Chen, Romain Laine, Ana Crespillo-Casado, Eduardo Pinho Melo, Ryo Ushioda, Kazuhiro Nagata, Clemens F Kaminski, Heather P Harding, David Ron

Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum.

Emerg Med J

Published Dec 17, 2014

Emergency department management of early sepsis: a national survey of emergency medicine and intensive care consultants.

Authors

Zoeb Jiwaji, Shirin Brady, Lauralyn A McIntyre, Alasdair Gray, Timothy S Walsh

Emergency department management of early sepsis: a national survey of emergency medicine and intensive care consultants.

J Neurosci

Published Nov 12, 2014

Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back.

Authors

Marco Brancaccio, Ryosuke Enoki, Cristina N Mazuski, Jeff Jones, Jennifer A Evans, Abdelhalim Azzi

Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back.

J Neurosci

Published Nov 12, 2014

Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back.

Authors

Marco Brancaccio, Ryosuke Enoki, Cristina N Mazuski, Jeff Jones, Jennifer A Evans, Abdelhalim Azzi

Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back.

Cell

Published Nov 06, 2014

Lessons from a failed γ-secretase Alzheimer trial.

Authors

Bart De Strooper

Lessons from a failed γ-secretase Alzheimer trial.

Cell

Published Nov 06, 2014

Lessons from a failed γ-secretase Alzheimer trial.

Authors

Bart De Strooper

Lessons from a failed γ-secretase Alzheimer trial.

Transfusion

Published Oct 31, 2014

Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial.

Authors

Zoeb Jiwaji, Kieran P Nunn, Andrew Conway-Morris, A John Simpson, Duncan Wyncoll, Adriano G Rossi, Timothy S Walsh

Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial.

Science

Published Sep 05, 2014

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.

Authors

Sarah Mizielinska, Sebastian Grönke, Teresa Niccoli, Charlotte E Ridler, Emma L Clayton, Anny Devoy, Thomas Moens, Frances E Norona, Ione O C Woollacott, Julian Pietrzyk, Karen Cleverley, Andrew J Nicoll, Stuart Pickering-Brown, Jacqueline Dols, Melissa Cabecinha, Oliver Hendrich, Pietro Fratta, Elizabeth M C Fisher, Linda Partridge, Adrian M Isaacs

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.

Science

Published Sep 05, 2014

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.

Authors

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.

Science

Published Aug 01, 2014

Interneurons. Fast-spiking, parvalbumin⁺ GABAergic interneurons: from cellular design to microcircuit function.

Authors

Hua Hu, Jian Gan, Peter Jonas

Interneurons. Fast-spiking, parvalbumin⁺ GABAergic interneurons: from cellular design to microcircuit function.

Science

Published Aug 01, 2014

Interneurons. Fast-spiking, parvalbumin⁺ GABAergic interneurons: from cellular design to microcircuit function.

Authors

Hua Hu, Jian Gan, Peter Jonas

Interneurons. Fast-spiking, parvalbumin⁺ GABAergic interneurons: from cellular design to microcircuit function.

Trends Genet

Published Jun 06, 2014

Tissue specificity in DNA repair: lessons from trinucleotide repeat instability.

Authors

Vincent Dion

Tissue specificity in DNA repair: lessons from trinucleotide repeat instability.

Neuron

Published May 21, 2014

The intersection of amyloid beta and tau at synapses in Alzheimer's disease.

Authors

Tara L Spires-Jones, Bradley T Hyman

The intersection of amyloid beta and tau at synapses in Alzheimer's disease.

Science

Published May 09, 2014

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal.

Authors

Marcela Rosas, Luke C Davies, Peter J Giles, Chia-Te Liao, Bashar Kharfan, Timothy C Stone, Valerie B O'Donnell, Donald J Fraser, Simon A Jones, Philip R Taylor

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal.

Neuron

Published Apr 16, 2014

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Authors

Soyon Hong, Beth L Ostaszewski, Ting Yang, Tiernan T O'Malley, Ming Jin, Katsuhiko Yanagisawa, Shaomin Li, Tim Bartels, Dennis J Selkoe

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Neuron

Published Apr 16, 2014

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Authors

Soyon Hong, Beth L Ostaszewski, Ting Yang, Tiernan T O'Malley, Ming Jin, Katsuhiko Yanagisawa, Shaomin Li, Tim Bartels, Dennis J Selkoe

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Science

Published Apr 11, 2014

PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.

Authors

Vanessa A Morais, Dominik Haddad, Katleen Craessaerts, Pieter-Jan De Bock, Jef Swerts, Sven Vilain, Liesbeth Aerts, Lut Overbergh, Anne Grünewald, Philip Seibler, Christine Klein, Kris Gevaert, Patrik Verstreken, Bart De Strooper

PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.

Science

Published Apr 11, 2014

PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.

Authors

PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.