Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

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- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Science (New York, N.Y.)
Published

PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress

Authors
Karinder K Brar, Daniel T Hughes, Jordan L Morris, Kelly Subramanian, Shivaani Krishna, Fei Gao, Lara-Sophie Rieder, Sebastian Uhrig, Joshua Freeman, Heather L Smith, Rebekkah Jukes-Jones, Edward Avezov, Jodi Nunnari, Julien Prudent, Adrian J Butcher, Giovanna R Mallucci
PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Clinical Manifestations

Authors
Emma-Jane Mallas, Michael Cb David, Hanim Karakoc, Chris Ml Tsoi, Paresh A Malhotra, Gregory Scott, David J Sharp
Clinical Manifestations
medRxiv : the preprint server for health sciences
Published

The CentiMarker Project: Standardizing Quantitative Alzheimer's disease Fluid Biomarkers for Biologic Interpretation

Authors
Guoqiao Wang, Yan Li, Chengjie Xiong, Yuchen Cao, Suzanne E Schindler, Eric McDade, Kaj Blennow, Oskar Hansson, Jeffrey L Dage, Clifford R Jack, Charlotte E Teunissen, Leslie M Shaw, Henrik Zetterberg, Ibanez Laura, Jigyasha Timsina, Cruchaga Carlos, DIAN-TU Study Team, Randall J Bateman
The CentiMarker Project: Standardizing Quantitative Alzheimer's disease Fluid Biomarkers for Biologic Interpretation
Acta Neuropathologica Communications
Published

Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype

Authors
Raphael Hesse, Maica Llavero Hurtado, Rosemary J. Jackson, Samantha L. Eaton, Abigail G. Herrmann, Marti Colom-Cadena, Makis Tzioras, Declan King, Jamie Rose, Jane Tulloch, Chris-Anne McKenzie, Colin Smith, Christopher M. Henstridge, Douglas Lamont, Thomas M. Wishart, Tara L. Spires-Jones
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype
Brain Communications
Published

Predictive blood biomarkers and brain changes associated with age-related cognitive decline

Authors
Tyler S Saunders, Francesca E Pozzolo, Amanda Heslegrave, Declan King, Robert I. McGeachan, Maxwell P Spires-Jones, Sarah E Harris, Craig Ritchie, Graciela Muniz-Terrera, Ian J Deary, Simon R Cox, Henrik Zetterberg, Tara L. Spires-Jones
Predictive blood biomarkers and brain changes associated with age-related cognitive decline
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Published

COVID-19 and stroke in women: impact on clinical, psychosocial and research aspects

Authors
Isabella Canavero, Benedetta Storti, Giulia Marinoni, Diana Aguiar De Souza, Elena Moro, Laura Gatti, Simona Sacco, Svetlana Lorenzano, Else C Sandset, Anna Poggesi, Tatiana Carrozzini, Giuliana Pollaci, Antonella Potenza, Gemma Gorla, Joanna M Wardlaw, Maria Luisa Zedde, Anna Bersano
COVID-19 and stroke in women: impact on clinical, psychosocial and research aspects
Frontiers in neuroscience
Published

Methodological challenges of measuring brain volumes and cortical thickness in idiopathic normal pressure hydrocephalus with a surface-based approach

Authors
Martina Del Giovane, Michael C B David, Magdalena A Kolanko, Anastasia Gontsarova, Thomas Parker, Adam Hampshire, David J Sharp, Paresh A Malhotra, Christopher Carswell
Methodological challenges of measuring brain volumes and cortical thickness in idiopathic normal pressure hydrocephalus with a surface-based approach
Curr Biol
Published

A REM-active basal ganglia circuit that regulates anxiety.

Authors
Wei Ba, Mathieu Nollet, Chunyu Yin, Xiao Yu, Sara Wong, Andawei Miao, Esteban J Beckwith, Edward C Harding, Ying Ma, Raquel Yustos, Alexei L Vyssotski, William Wisden, Nicholas P Franks
A REM-active basal ganglia circuit that regulates anxiety.
Trials
Published

Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event

Authors
Mia S Tackney, Amber Steele, Joseph Newman, Marie-Christine Fritzsche, Federica Lucivero, Zarnie Khadjesari, Jennifer Lynch, Rosemary A Abbott, Vicki S Barber, James R Carpenter, Bethan Copsey, Elin H Davies, William G Dixon, Lisa Fox, Javier González, Jessica Griffiths, Chloe H L Hinchliffe, Magdalena A Kolanko, Dylan McGagh, Aryelly Rodriguez, George Roussos, Karen B E So, Louise Stanton, Mark Toshner, Frances Varian, Paula R Williamson, Belay B Yimer, Sofía S Villar
Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event