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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Cerebrovascular diseases (Basel, Switzerland)
Published

Perihaematomal Oedema Evolution over 2 Weeks after Spontaneous Intracerebral Haemorrhage and Association with Outcome: A Prospective Cohort Study

Authors
Neshika Samarasekera, Karen Ferguson, Adrian Robert Parry-Jones, Mark Rodrigues, James Loan, Tom J Moullaali, Jeremy Hughes, Laura Shoveller, Joanna Wardlaw, Barry McColl, Stuart M Allan, Magdy Selim, John Norrie, Colin Smith, Rustam Al-Shahi Salman
Perihaematomal Oedema Evolution over 2 Weeks after Spontaneous Intracerebral Haemorrhage and Association with Outcome: A Prospective Cohort Study
Nature cell biology
Published

VAMP2 regulates phase separation of α-synuclein

Authors
Aishwarya Agarwal, Aswathy Chandran, Farheen Raza, Irina-Maria Ungureanu, Christine Hilcenko, Katherine Stott, Nicholas A Bright, Nobuhiro Morone, Alan J Warren, Janin Lautenschläger
VAMP2 regulates phase separation of α-synuclein
Current biology : CB
Published

A REM-active basal ganglia circuit that regulates anxiety

Authors
Wei Ba, Mathieu Nollet, Chunyu Yin, Xiao Yu, Sara Wong, Andawei Miao, Esteban J Beckwith, Edward C Harding, Ying Ma, Raquel Yustos, Alexei L Vyssotski, William Wisden, Nicholas P Franks
A REM-active basal ganglia circuit that regulates anxiety
Sci Adv
Published

The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1.

Authors
Emil K Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H Reynolds, James R Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H Douse, Anita Adami, Diahann A M Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W Wood, Henry Houlden, Harpreet Saini, Carla F Bento, John Hardy, Mina Ryten
The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1.
Communications medicine
Published

Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium

Authors
Mari Aksnes, Mari Haavig Schibstad, Farrukh Abbas Chaudhry, Bjørn Erik Neerland, Gideon Caplan, Ingvild Saltvedt, Rannveig S Eldholm, Marius Myrstad, Trine Holt Edwin, Karin Persson, Ane-Victoria Idland, Christian Thomas Pollmann, Roy Bjørkholt Olsen, Torgeir Bruun Wyller, Henrik Zetterberg, Emma Cunningham, Leiv Otto Watne
Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant pathologies

Authors
Andreja Emeršič, Nicholas J Ashton, Agathe Vrillon, Juan Lantero-Rodriguez, Jernej Mlakar, Milica Gregorič Kramberger, Fernando Gonzalez-Ortiz, Przemysław R Kac, Maciej Dulewicz, Jörg Hanrieder, Eugeen Vanmechelen, Uroš Rot, Henrik Zetterberg, Thomas K Karikari, Saša Čučnik, Kaj Blennow
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant pathologies
Science advances
Published

The annotation of <em>GBA1</em> has been concealed by its protein-coding pseudogene <em>GBAP1</em>

Authors
Emil K Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H Reynolds, James R Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H Douse, Anita Adami, Diahann A M Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W Wood, Henry Houlden, Harpreet Saini, Carla F Bento, John Hardy, Mina Ryten
The annotation of <em>GBA1</em> has been concealed by its protein-coding pseudogene <em>GBAP1</em>
NPJ Parkinson's disease
Published

Author Correction: Lysosomal and synaptic dysfunction markers in longitudinal cerebrospinal fluid of de novo Parkinson's disease

Authors
Michael Bartl, Johanna Nilsson, Mohammed Dakna, Sandrina Weber, Sebastian Schade, Mary Xylaki, Bárbara Fernandes Gomes, Marielle Ernst, Maria-Lucia Muntean, Friederike Sixel-Döring, Claudia Trenkwalder, Henrik Zetterberg, Ann Brinkmalm, Brit Mollenhauer
Author Correction: Lysosomal and synaptic dysfunction markers in longitudinal cerebrospinal fluid of de novo Parkinson's disease
BMJ open
Published

Protocol for a double-blind placebo-controlled randomised controlled trial assessing the impact of oral semaglutide in amyloid positivity (ISAP) in community dwelling UK adults

Authors
Ivan Koychev, Amanda I Adler, Paul Edison, Brian Tom, Joanne E Milton, Joe Butchart, Adam Hampshire, Charles Marshall, Elizabeth Coulthard, Henrik Zetterberg, Peter Hellyer, Francesca Cormack, Benjamin R Underwood, Catherine J Mummery, Rury R Holman
Protocol for a double-blind placebo-controlled randomised controlled trial assessing the impact of oral semaglutide in amyloid positivity (ISAP) in community dwelling UK adults
Cerebral cortex (New York, N.Y. : 1991)
Published

Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study

Authors
Elise Beckers, Maxime Van Egroo, Nicholas J Ashton, Kaj Blennow, Gilles Vandewalle, Henrik Zetterberg, Benedikt A Poser, Heidi I L Jacobs
Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study