Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Elecsys pTau217 plasma immunoassay detection of amyloid pathology in clinical cohorts

Authors
Derrek P Hibar, Alina Bauer, Christina Rabe, Niels Borlinghaus, Alexander Jethwa, Gwendlyn Kollmorgen, Annunziata Di Domenico, Henrik Zetterberg, Kaj Blennow, Colin L Masters, Reisa A Sperling, Tobias Bittner
Elecsys pTau217 plasma immunoassay detection of amyloid pathology in clinical cohorts
Alzheimer's research & therapy
Published

Double cutoff strategies for plasma pTau217 to predict Tau PET positivity across multiple assay platforms: Tau-enriched and Tau-scarce cohorts for cost-effective clinical use

Authors
Heekyoung Kang, Yuna Gu, Jungah Lee, Soyeon Yoon, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Theresa A Day, Michael W Weiner, Daeun Shin, Sohyun Yim, Seonghyeon Kim, Hee Kyung Park, Min Young Chun, Eun Hye Lee, Jun Pyo Kim, Hee Jin Kim, Duk L Na, Hyemin Jang, Sang Won Seo, ADNI and K-ROAD study group
Double cutoff strategies for plasma pTau217 to predict Tau PET positivity across multiple assay platforms: Tau-enriched and Tau-scarce cohorts for cost-effective clinical use
Psychological medicine
Published

Subjective estimation of cognitive function in mild cognitive impairment: relationship with neurodegenerative and non-degenerative factors

Authors
Calum A Hamilton, Peter Gallagher, Paul C Donaghy, Joanna Ciafone, Michael Firbank, Gemma Greenfinch, Amanda Heslegrave, Henrik Zetterberg, John-Paul Taylor, Louise M Allan, John T O'Brien, Alan J Thomas
Subjective estimation of cognitive function in mild cognitive impairment: relationship with neurodegenerative and non-degenerative factors
Lancet Neurol
Published

Azathioprine for the treatment of early Parkinson's disease (AZA-PD): a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial.

Authors
Julia C Greenland, Kerry Dresser, Emma Cutting, Rachel Donegan, Simon Bond, Sarah J Crisp, Kirsten M Scott, Zanna J Voysey, Jonathan Holbrook, Lakmini Kahanawita, Reiss Pal, Marta Camacho, Alexander R D Peattie, Lennart R B Spindler, Young T Hong, Tim D Fryer, Caroline H Williams-Gray
Azathioprine for the treatment of early Parkinson's disease (AZA-PD): a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial.
Alzheimer's & dementia (New York, N. Y.)
Published

Baseline characteristics from evoke and evoke+: Two phase 3 randomized placebo-controlled trials of semaglutide in participants with early-stage symptomatic Alzheimer's disease

Authors
Philip Scheltens, Alireza Atri, Howard H Feldman, Henrik Zetterberg, Mary Sano, Peter Johannsen, Teresa León Colombo, Lars Bardtrum, Rose Jeppesen, Charlotte T Hansen, Jeffrey L Cummings
Baseline characteristics from evoke and evoke+: Two phase 3 randomized placebo-controlled trials of semaglutide in participants with early-stage symptomatic Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Biomarkers

Authors
Julie E Oomens, Theresa M Harrison, Jeffrey L Dage, Kristen A Russ, Henrik Zetterberg, William J Jagust, Tatiana M Foroud, Sarah Biber, Elizabeth C Mormino, Sterling C Johnson
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Biomarkers

Authors
Jakub Vávra, Wiebke Traichel, Andrea Benedet, Hanna Huber, Kaj Blennow, Laia Montoliu-Gaya, Nicholas Ashton, Henrik Zetterberg
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Biomarkers

Authors
Magdalena A Kolanko, Raphaella Jackson, Eyal Soreq, Michael Cb David, Kirsten Jensen, Amanda J Heslegrave, Martin Tran, Michael Crone, Sarah Daniels, David Wingfield, Henrik Zetterberg, Paul Freemont, David J Sharp
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Biomarkers

Authors
Annalise E Miner, Nicholas J Ashton, Henrik Zetterberg, Kaj Blennow, Jenna R Groh, Yorghos Tripodis, Charles Adler, Laura Balcer, Charles B Bernick, Elaine R Peskind, Breton M Asken, Jeremy A Tanner, Gil D Rabinovici, Sarah J Banks, William B Barr, Jennifer V Wethe, Robert C Cantu, David W Dodick, Jesse Mez, Joseph N Palmisano, Brett Martin, Thor D Stein, Ann C McKee, Jeffrey L Cummings, Martha E Shenton, Eric M Reiman, Robert A Stern, Michael L Alosco
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Biomarkers

Authors
Aitana Sogorb-Esteve, Sophia Weiner, Joel Simrén, Imogen J Swift, Kaj Blennow, Henrik Zetterberg, Jonathan D Rohrer, Johan Gobom
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Biomarkers

Authors
Corey J Bolton, Panpan Zhang, Amalia Jo Peterson, Dandan Liu, Timothy J Hohman, Kaj Blennow, Henrik Zetterberg, Angela L Jefferson
Biomarkers
bioRxiv : the preprint server for biology
Published

The craniofacial shape of modern humans embodies genomic signatures of evolution, diversity, and clinical conditions

Authors
Seppe Goovaerts, Jay Devine, Nina Claessens, Sameer Gabbita, Jolien Deprest, Kaat Pauwels, Noah Herrick, Jaaved Mohammed, Aurélien Mounier, Tamar Sofer, Hannah K Long, Ullrich Bartsch, Benedikt Hallgrímsson, Sarah J Lewis, Stephen Richmond, Sarah Bauermeister, Susan Walsh, John R Shaffer, Mark D Shriver, Sahin Naqvi, Joanna Wysocka, Toomas Kivisild, Seth M Weinberg, Peter Claes
The craniofacial shape of modern humans embodies genomic signatures of evolution, diversity, and clinical conditions