Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Current biology : CB
Published

The blood-brain barrier

Authors
Audrey Chagnot, Axel Montagne
The blood-brain barrier
European journal of nuclear medicine and molecular imaging
Published

Comparing and combining TSPO-PET tracers in tauopathies

Authors
Harry Crook, Nicolai Franzmeier, Nesrine Rahmouni, Johannes S Gnörich, Tim D Fryer, Young T Hong, Sebastian N Roemer-Cassiano, Carla Palleis, Alexandra Strauss, P Simon Jones, Franklin I Aigbirhio, Robert Hopewell, Boris-Stephan Rauchmann, Gassan Massarweh, Robert Perneczky, Johannes Levin, Günter U Höglinger, James B Rowe, John T O'Brien, Pedro Rosa-Neto, Matthias Brendel, Maura Malpetti
Comparing and combining TSPO-PET tracers in tauopathies
Neurology
Published

Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease

Authors
David López-Martos, Marc Suárez-Calvet, Marta Milà-Alomà, Juan Domingo Gispert, Gemma Salvadó, Anna Brugulat-Serrat, Mahnaz Shekari, Carolina Minguillon, Henrik Zetterberg, Kaj Blennow, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides, ALFA study
Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease
Molecular neurodegeneration
Published

Synaptic dysfunction and glial activation markers throughout aging and early neurodegeneration: a longitudinal CSF biomarker-based study

Authors
Mariana I Muñoz-García, Yuetiva Deming, Ferran Lugo-Hernández, Sterling Johnson, Sanjay Asthana, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Cynthia Carlsson, Ozioma C Okonkwo, David Pérez-Martinez, Alberto Villarejo-Galende, Kaj Blennow, Marc Suárez-Calvet, Henrik Zetterberg, Barbara B Bendlin, Estrella Morenas-Rodríguez
Synaptic dysfunction and glial activation markers throughout aging and early neurodegeneration: a longitudinal CSF biomarker-based study
Schizophrenia research
Published

The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia

Authors
Maria E Dimitriades, Eve Schumacher, Janani Arudchelvam, Sara Fattinger, Salome Kurth, Fiona Pugin, Flavia Wehrle, Valeria Jaramillo, Carina Volk, Sven Leach, Ashura Buckley, David I Driver, Andjela Markovic, Judith L Rapoport, Leila Tarokh, Reto Huber, Miriam Gerstenberg
The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia
Nature cell biology
Published

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome

Authors
Rabia R Khawaja, Ernesto Griego, Kristen Lindenau, Asma Salek, Jessica Gambardella, Aurora Scrivo, Hannah R Monday, Mathieu Bourdenx, Jesús Madero-Pérez, Zohaib N Khan, Bhakti Chavda, Ronald Cutler, Sarah Graff, Simone Sidoli, Gaetano Santulli, Laura Santambrogio, Inmaculada Tasset, Susmita Kaushik, Li Gan, Pablo E Castillo, Ana Maria Cuervo
Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease

Authors
Eleonora M Vromen, Senne B Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Lars Bertram, Johannes Streffer, Simon Lovestone, Stephanie J B Vos, Mikel Tainta, Yvonne Freund-Levi, Lutz Frölich, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Frans Verhey, Rik Vandenberghe, Jolien Schaeverbeke, Kaj Blennow, Sven J van der Lee, Philip Scheltens, Yolande A L Pijnenburg, Wiesje M van der Flier, Charlotte E Teunissen, Henrik Zetterberg, Pieter Jelle Visser, Betty Tijms
Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease
Molecular neurodegeneration
Published

Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways

Authors
Bjørn-Eivind Kirsebom, Johanna Nilsson, Ellen Vromen, Peter Mikael Arnesen, Atle Bjørnerud, Ann Brinkmalm, Geir Bråthen, Gøril Rolfseng Grøntvedt, Jonas Jarholm, Kaja Nordengen, Lene Pålhaugen, Per Selnes, Nikias Siafarikas, Ragnhild Eide Skogseth, Sandra Tecelão, Knut Waterloo, Panpan You, Henrik Zetterberg, Dag Aarsland, Betty Tijms, Pieter Jelle Visser, Kaj Blennow, Tormod Fladby
Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways
Movement disorders : official journal of the Movement Disorder Society
Published

Systematic Review with Meta-Analysis of Biofluid Markers for Huntington's Disease

Authors
Jane S Paulsen, Natalie A Bovin, Jordan D Clemsen, Alexander Weiss, Abigail M Key, Monica L Janz, Alex Pinto, Deven K Burks, Henrik Zetterberg, Kathleen M Shannon
Systematic Review with Meta-Analysis of Biofluid Markers for Huntington's Disease