Skip to main content
Search
Main content

Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Clinical chemistry and laboratory medicine
Published

The correlation of albumin with total protein concentrations in cerebrospinal fluid across three automated analysers - relevance to the diagnosis of subarachnoid haemorrhage in clinical chemistry practice

Authors
Marcus Clarin, Elin Gustafsson, Carina Gustafsson, Maria Lohmander, Henrik Zetterberg
The correlation of albumin with total protein concentrations in cerebrospinal fluid across three automated analysers - relevance to the diagnosis of subarachnoid haemorrhage in clinical chemistry practice
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Head-to-head comparison of leading blood tests for Alzheimer's disease pathology

Authors
Suzanne E Schindler, Kellen K Petersen, Benjamin Saef, Duygu Tosun, Leslie M Shaw, Henrik Zetterberg, Jeffrey L Dage, Kyle Ferber, Gallen Triana-Baltzer, Lei Du-Cuny, Yan Li, Janaky Coomaraswamy, Michael Baratta, Yulia Mordashova, Ziad S Saad, David L Raunig, Nicholas J Ashton, Emily A Meyers, Carrie E Rubel, Erin G Rosenbaugh, Anthony W Bannon, William Z Potter, Alzheimer's Disease Neuroimaging Initiative (ADNI) Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer's Disease Project Team
Head-to-head comparison of leading blood tests for Alzheimer's disease pathology
Journal of neurology, neurosurgery, and psychiatry
Published

Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: the ADVANCE study

Authors
Neil Sn Graham, Grace Blissitt, Karl Zimmerman, Lydia Orton, Daniel Friedland, Emma Coady, Rhiannon Laban, Elena Veleva, Amanda J Heslegrave, Henrik Zetterberg, Susie Schofield, Nicola T Fear, Christopher J Boos, Anthony M J Bull, Alexander Bennett, David J Sharp, ADVANCE Study
Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: the ADVANCE study
European journal of neurology
Published

Pre-hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT-2 trial

Authors
Jason P Appleton, Mark Dixon, Lisa J Woodhouse, Craig S Anderson, Sandeep Ankolekar, Lesley Cala, Timothy J England, Peter J Godolphin, Kailash Krishnan, Grant Mair, Keith W Muir, John Potter, Chris I Price, Marc Randall, Thompson G Robinson, Christine Roffe, Peter M Rothwell, Else Charlotte Sandset, Jeffrey L Saver, A Niroshan Siriwardena, Joanna M Wardlaw, Nikola Sprigg, Philip M Bath, RIGHT‐2 Investigators
Pre-hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT-2 trial
Molecular psychiatry
Published

Sex/gender effects of glial reactivity on preclinical Alzheimer's disease pathology

Authors
Clara Vila-Castelar, Muge Akinci, Eleni Palpatzis, Pablo Aguilar-Dominguez, Gregory Operto, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Kaj Blennow, Henrik Zetterberg, Carles Falcon, Karine Fauria, Juan Domingo Gispert, Oriol Grau-Rivera, Marc Suárez-Calvet, Eider M Arenaza-Urquijo, ALFA study
Sex/gender effects of glial reactivity on preclinical Alzheimer's disease pathology
Aging Cell
Published

Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons.

Authors
James N Sleigh, Francesca Mattedi, Sandy Richter, Emily Annuario, Kristal Ng, I Emilie Steinmark, Iveta Ivanova, István L Darabán, Parth P Joshi, Elena R Rhymes, Shirwa Awale, Gokhan Yahioglu, Jacqueline C Mitchell, Klaus Suhling, Giampietro Schiavo, Alessio Vagnoni
Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons.
medRxiv : the preprint server for health sciences
Published

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

Authors
Luis M García-Marín, Adrian I Campos, Santiago Diaz-Torres, Jill A Rabinowitz, Zuriel Ceja, Brittany L Mitchell, Katrina L Grasby, Jackson G Thorp, Ingrid Agartz, Saud Alhusaini, David Ames, Philippe Amouyel, Ole A Andreassen, Konstantinos Arfanakis, Alejandro Arias Vasquez, Nicola J Armstrong, Lavinia Athanasiu, Mark E Bastin, Alexa S Beiser, David A Bennett, Joshua C Bis, Marco Pm Boks, Dorret I Boomsma, Henry Brodaty, Rachel M Brouwer, Jan K Buitelaar, Ralph Burkhardt, Wiepke Cahn, Vince D Calhoun, Owen T Carmichael, Mallar Chakravarty, Qiang Chen, Christopher R K Ching, Sven Cichon, Benedicto Crespo-Facorro, Fabrice Crivello, Anders M Dale, George Davey Smith, Eco Jc de Geus, Philip L De Jager, Greig I de Zubicaray, Stéphanie Debette, Charles DeCarli, Chantal Depondt, Sylvane Desrivières, Srdjan Djurovic, Stefan Ehrlich, Susanne Erk, Thomas Espeseth, Guillén Fernández, Irina Filippi, Simon E Fisher, Debra A Fleischman, Evan Fletcher, Myriam Fornage, Andreas J Forstner, Clyde Francks, Barbara Franke, Tian Ge, Aaron L Goldman, Hans J Grabe, Robert C Green, Oliver Grimm, Nynke A Groenewold, Oliver Gruber, Vilmundur Gudnason, Asta K Håberg, Unn K Haukvik, Andreas Heinz, Derrek P Hibar, Saima Hilal, Jayandra J Himali, Beng-Choon Ho, David F Hoehn, Pieter J Hoekstra, Edith Hofer, Wolfgang Hoffmann, Avram J Holmes, Georg Homuth, Norbert Hosten, M Kamran Ikram, Jonathan C Ipser, Clifford R Jack, Neda Jahanshad, Erik G Jönsson, Rene S Kahn, Ryota Kanai, Marieke Klein, Maria J Knol, Lenore J Launer, Stephen M Lawrie, Stephanie Le Hellard, Phil H Lee, Hervé Lemaître, Shuo Li, David Cm Liewald, Honghuang Lin, W T Longstreth, Oscar L Lopez, Michelle Luciano, Pauline Maillard, Andre F Marquand, Nicholas G Martin, Jean-Luc Martinot, Karen A Mather, Venkata S Mattay, Katie L McMahon, Patrizia Mecocci, Ingrid Melle, Andreas Meyer-Lindenberg, Nazanin Mirza-Schreiber, Yuri Milaneschi, Thomas H Mosley, Thomas W Mühleisen, Bertram Müller-Myhsok, Susana Muñoz Maniega, Matthias Nauck, Kwangsik Nho, Wiro J Niessen, Markus M Nöthen, Paul A Nyquist, Jaap Oosterlaan, Massimo Pandolfo, Tomas Paus, Zdenka Pausova, Brenda Wjh Penninx, G Bruce Pike, Bruce M Psaty, Benno Pütz, Simone Reppermund, Marcella D Rietschel, Shannon L Risacher, Nina Romanczuk-Seiferth, Rafael Romero-Garcia, Gennady V Roshchupkin, Jerome I Rotter, Perminder S Sachdev, Philipp G Sämann, Arvin Saremi, Muralidharan Sargurupremraj, Andrew J Saykin, Lianne Schmaal, Helena Schmidt, Reinhold Schmidt, Peter R Schofield, Markus Scholz, Gunter Schumann, Emanuel Schwarz, Li Shen, Jean Shin, Sanjay M Sisodiya, Albert V Smith, Jordan W Smoller, Hilkka S Soininen, Vidar M Steen, Dan J Stein, Jason L Stein, Sophia I Thomopoulos, Arthur W Toga, Diana Tordesillas-Gutiérrez, Julian N Trollor, Maria C Valdes-Hernandez, Dennis van 't Ent, Hans van Bokhoven, Dennis van der Meer, Nic Ja van der Wee, Javier Vázquez-Bourgon, Dick J Veltman, Meike W Vernooij, Arno Villringer, Louis N Vinke, Henry Völzke, Henrik Walter, Joanna M Wardlaw, Daniel R Weinberger, Michael W Weiner, Wei Wen, Lars T Westlye, Eric Westman, Tonya White, A Veronica Witte, Christiane Wolf, Jingyun Yang, Marcel P Zwiers, M Arfan Ikram, Sudha Seshadri, Paul M Thompson, Claudia L Satizabal, Sarah E Medland, Miguel E Rentería
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
medRxiv : the preprint server for health sciences
Published

Gut-Brain Nexus: Mapping Multi-Modal Links to Neurodegeneration at Biobank Scale

Authors
Mohammad Shafieinouri, Samantha Hong, Artur Schuh, Mary B Makarious, Rodrigo Sandon, Paul Suhwan Lee, Emily Simmonds, Hirotaka Iwaki, Gracelyn Hill, Cornelis Blauwendraat, Valentina Escott-Price, Yue A Qi, Alastair J Noyce, Armando Reyes-Palomares, Hampton L Leonard, Malu Tansey, Anant Dadu, Faraz Faghri, Andrew Singleton, Mike A Nalls, Kristin S Levine, Sara Bandres-Ciga
Gut-Brain Nexus: Mapping Multi-Modal Links to Neurodegeneration at Biobank Scale
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting

Authors
Dhamidhu Eratne, Matthew J Y Kang, Courtney Lewis, Christa Dang, Charles B Malpas, Michael Keem, Jasleen Grewal, Vladimir Marinov, Amy Coe, Cath Kaylor-Hughes, Thomas Borchard, Chhoa Keng-Hong, Alexandra Waxmann, Burcu Saglam, Tomas Kalincik, Richard Kanaan, Wendy Kelso, Andrew Evans, Sarah Farrand, Samantha Loi, Mark Walterfang, Christiane Stehmann, Qiao-Xin Li, Steven Collins, Colin L Masters, Alexander F Santillo, Henrik Zetterberg, Kaj Blennow, Samuel F Berkovic, Dennis Velakoulis, MiND Study Group
Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting
Nature communications
Published

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy

Authors
Amy-Jayne Hutchings, Bita Hambrecht, Alexander Veh, Neha Jadhav Giridhar, Abdolhossein Zare, Christina Angerer, Thorben Ohnesorge, Maren Schenke, Bhuvaneish T Selvaraj, Siddharthan Chandran, Jared Sterneckert, Susanne Petri, Bettina Seeger, Michael Briese, Christian Stigloher, Thorsten Bischler, Andreas Hermann, Markus Damme, Michael Sendtner, Patrick Lüningschrör
Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy
Nature reviews. Neurology
Published

Fluid biomarkers of chronic traumatic brain injury

Authors
Susanna Friberg, Caroline Lindblad, Frederick A Zeiler, Henrik Zetterberg, Tobias Granberg, Per Svenningsson, Fredrik Piehl, Eric P Thelin
Fluid biomarkers of chronic traumatic brain injury
Science (New York, N.Y.)
Published

Creation of de novo cryptic splicing for ALS and FTD precision medicine

Authors
Oscar G Wilkins, Max Z Y J Chien, Josette J Wlaschin, Simone Barattucci, Peter Harley, Francesca Mattedi, Puja R Mehta, Maria Pisliakova, Eugeni Ryadnov, Matthew J Keuss, David Thompson, Holly Digby, Lea Knez, Rebecca L Simkin, Juan Antinao Diaz, Matteo Zanovello, Anna-Leigh Brown, Annalucia Darbey, Rajvinder Karda, Elizabeth M C Fisher, Thomas J Cunningham, Claire E Le Pichon, Jernej Ule, Pietro Fratta
Creation of de novo cryptic splicing for ALS and FTD precision medicine
Stroke and vascular neurology
Published

Definitions of white matter hyperintensity change: impact on estimates of progression and regression

Authors
Angela C C Jochems, Susana Muñoz Maniega, Una Clancy, Carmen Arteaga Reyes, Daniela Jaime Garcia, Maria Del C Valdés Hernández, Francesca M Chappell, Gayle Barclay, Charlotte Jardine, Donna McIntyre, Iona Gerrish, Stewart Wiseman, Michael S Stringer, Michael J Thrippleton, Fergus Doubal, Joanna M Wardlaw
Definitions of white matter hyperintensity change: impact on estimates of progression and regression