Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

- Research

Genetic changes in brain cells link ageing and Alzheimer’s

Genetic differences that contribute to how long a person will live and their risk of Alzheimer’s disease have been identified in a new study led...

Learn more Genetic changes in brain cells link ageing and Alzheimer’s
Stroke and vascular neurology
Published

Definitions of white matter hyperintensity change: impact on estimates of progression and regression

Authors
Angela C C Jochems, Susana Muñoz Maniega, Una Clancy, Carmen Arteaga Reyes, Daniela Jaime Garcia, Maria Del C Valdés Hernández, Francesca M Chappell, Gayle Barclay, Charlotte Jardine, Donna McIntyre, Iona Gerrish, Stewart Wiseman, Michael S Stringer, Michael J Thrippleton, Fergus Doubal, Joanna M Wardlaw
Definitions of white matter hyperintensity change: impact on estimates of progression and regression
Brain communications
Published

Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury

Authors
Alex Tsui, Benjamin Johnstone, Amanda Heslegrave, Henrik Zetterberg, Leiv Otto Watne, Bjørn Erik Neerland, Maria Krogseth, Colm Cunningham, Alasdair MacLullich, Graciela Muniz Terrera, Daniel Davis, Gideon Caplan
Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players

Authors
Annalise E Miner, Jenna R Groh, Yorghos Tripodis, Charles H Adler, Laura J Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine Peskind, Nicholas J Ashton, Charles E Gaudet, Brett Martin, Joseph N Palmisano, Sarah J Banks, William B Barr, Jennifer V Wethe, Robert C Cantu, David W Dodick, Douglas I Katz, Jesse Mez, Suzan van Amerongen, Jeffrey L Cummings, Martha E Shenton, Eric M Reiman, Robert A Stern, Michael L Alosco, DIAGNOSE CTE Research Project
Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players
Nature medicine
Published

Increased frequency of repeat expansion mutations across different populations

Authors
Kristina Ibañez, Bharati Jadhav, Matteo Zanovello, Delia Gagliardi, Christopher Clarkson, Stefano Facchini, Paras Garg, Alejandro Martin-Trujillo, Scott J Gies, Valentina Galassi Deforie, Anupriya Dalmia, Davina J Hensman Moss, Jana Vandrovcova, Clarissa Rocca, Loukas Moutsianas, Chiara Marini-Bettolo, Helen Walker, Chris Turner, Maryam Shoai, Jeffrey D Long, Pietro Fratta, Douglas R Langbehn, Sarah J Tabrizi, Mark J Caulfield, Andrea Cortese, Valentina Escott-Price, John Hardy, Henry Houlden, Andrew J Sharp, Arianna Tucci
Increased frequency of repeat expansion mutations across different populations
Nat Med
Published

Increased frequency of repeat expansion mutations across different populations.

Authors
Kristina Ibañez, Bharati Jadhav, Matteo Zanovello, Delia Gagliardi, Christopher Clarkson, Stefano Facchini, Paras Garg, Alejandro Martin-Trujillo, Scott J Gies, Valentina Galassi Deforie, Anupriya Dalmia, Davina J Hensman Moss, Jana Vandrovcova, Clarissa Rocca, Loukas Moutsianas, Chiara Marini-Bettolo, Helen Walker, Chris Turner, Maryam Shoai, Jeffrey D Long, Pietro Fratta, Douglas R Langbehn, Sarah J Tabrizi, Mark J Caulfield, Andrea Cortese, Valentina Escott-Price, John Hardy, Henry Houlden, Andrew J Sharp, Arianna Tucci
Increased frequency of repeat expansion mutations across different populations.
BMC geriatrics
Published

Experiences with home monitoring technology in older adults with traumatic brain injury: a qualitative study

Authors
Megan E Parkinson, Rebecca M Smith, Karen Tanious, Francesca Curtis, Rebecca Doherty, Lorena Colon, Lucero Chena, Sophie C Horrocks, Matthew Harrison, Michael B Fertleman, Melanie Dani, Payam Barnaghi, David J Sharp, UK Dementia Research Institute Care Research & Technology Research Group, Lucia M Li
Experiences with home monitoring technology in older adults with traumatic brain injury: a qualitative study
Nature communications
Published

NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity

Authors
Susan Kilgas, Aleem Syed, Patrick Toolan-Kerr, Michelle L Swift, Shrabasti Roychoudhury, Aniruddha Sarkar, Sarah Wilkins, Mikayla Quigley, Anna R Poetsch, Maria Victoria Botuyan, Gaofeng Cui, Georges Mer, Jernej Ule, Pascal Drané, Dipanjan Chowdhury
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Practical neurology
Published

Repeat expansion disorders

Authors
Zhongbo Chen, Huw R Morris, James Polke, Nicholas W Wood, Sonia Gandhi, Mina Ryten, Henry Houlden, Arianna Tucci
Repeat expansion disorders
iScience
Published

Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19

Authors
Marina O Rontogianni, Dipender Gill, Emmanouil Bouras, Alexandros-Georgios Asimakopoulos, Ioanna Tzoulaki, Ville Karhunen, Terho Lehtimäki, Olli Raitakari, Matthias Wielscher, Veikko Salomaa, Sirpa Jalkanen, Marko Salmi, Markku Timonen, James Yarmolinsky, Jing Chen, Martin D Tobin, Abril G Izquierdo, Karl-Heinz Herzig, Anne E Ioannides, Marjo-Riitta Jarvelin, Abbas Dehghan, Konstantinos K Tsilidis
Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19
PLoS pathogens
Published

Changes in cerebrospinal fluid proteins across the spectrum of untreated and treated chronic HIV-1 infection

Authors
Zicheng Hu, Paola Cinque, Ameet Dravid, Lars Hagberg, Aylin Yilmaz, Henrik Zetterberg, Dietmar Fuchs, Johanna Gostner, Kaj Blennow, Serena S Spudich, Laura Kincer, Shuntai Zhou, Sarah Beth Joseph, Ronald Swanstrom, Richard W Price, Magnus Gisslén
Changes in cerebrospinal fluid proteins across the spectrum of untreated and treated chronic HIV-1 infection